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Index > Protein center > IGFBP3(Gene name) > Bovine
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  • IGFBP3 (Gene name),
  • Insulin-like growth factor-binding protein 3 (Protein name ),  IBP3_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IGFBP3;
    Protein name:
    Insulin-like growth factor-binding protein 3(IBP-3;IGF-binding protein 3;IGFBP-3);
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Binds IGF2 more than IGF1. Forms a ternary complex of about 140 to 150 kDa with IGF1 or IGF2 and a 85 kDa glycoprotein (ALS). Interacts with XLKD1.
    Function:
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    291
    Sequence:
    50:
    MLRARPALWA | AALTALTLLR | GPPAARAGAG | TMGAGPVVRC | EPCDARAVAQ | 
    100:
    CAPPPPSPPC | AELVREPGCG | CCLTCALREG | QPCGVYTERC | GSGLRCQPPP | 
    150:
    GDPRPLQALL | DGRGLCANAS | AVGRLRPYLL | PSASGNGSES | EEDHSMGSTE | 
    200:
    NQAGPSTHRV | PVSKFHPIHT | KMDVIKKGHA | KDSQRYKVDY | ESQSTDTQNF | 
    250:
    SSESKRETEY | GPCRREMEDT | LNHLKFLNML | SPRGIHIPNC | DKKGFYKKKQ | 
    291:
    CRPSKGRKRG | FCWCVDKYGQ | PLPGFDVKGK | GDVHCYSMES | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine IBP-3
    Cat.:
    E0054r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine IBP-3
    Cat.:
    E0054b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine IBP-3
    Cat.:
    E0054h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine IBP-3
    Cat.:
    E0054m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine IBP-3
    Cat.:
    E0054p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine IBP-3
    Cat.:
    U0054p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine IBP-3
    Cat.:
    U0054m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine IBP-3
    Cat.:
    U0054h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine IBP-3
    Cat.:
    U0054b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine IBP-3
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Bovine IBP-3
    Cat.:
    P0054Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine IBP-3
    Polyclonal Antibody for Bovine IBP-3
    Cat.:
    P0054Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine IBP-3
    Polyclonal Antibody for Bovine IBP-3
    Cat.:
    P0054Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine IBP-3
    Monoclonal Antibody for Bovine IBP-3
    Monoclonal Antibody for Bovine IBP-3
    Monoclonal Antibody for Bovine IBP-3
    Monoclonal Antibody for Bovine IBP-3
    Protein for Bovine IBP-3
    Protein for Bovine IBP-3
    Protein for Bovine IBP-3
    Protein for Bovine IBP-3
    Protein for Bovine IBP-3

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    References
    1. 1.
      "Cloning and characterization of bovine insulin-like growth factor binding protein-3 (bIGFBP-3)."
      Spratt S.K. , Tatsuno G.P. , Sommer A.
      Biochem. Biophys. Res. Commun.177:1025-1032(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Bovine insulin-like growth factor binding protein-3: organization of the chromosomal gene and functional analysis of its promoter."
      Erondu N.E. , Toland B. , Boes M. , Dake B. , Moser D.R. , Bar R.S.
      Endocrinology138:2856-2862(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Liver.
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal lung.
    4. 4.
      "Structural and biological characterization of bovine insulin-like growth factor binding protein-3."
      Conover C.A. , Ronk M. , Lombana F. , Powell D.R.
      Endocrinology127:2795-2803(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-52
    5. 5.
      "A novel polymorphism in the bovine insulin-like growth factor binding protein-3 (IGFBP3) gene."
      Maciulla J.H. , Zhang H.M. , Denise S.K.
      Anim. Genet.28:375-375(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 194-266
    6. 6.
      "Cloning, expression, characterization and role in autocrine cell growth of cell surface retention sequence binding protein-1."
      Huang S.S. , Tang F.-M. , Huang Y.-H. , Liu I.-H. , Hsu S.-C. , Chen S.-T. , Huang J.S.
      J. Biol. Chem.278:43855-43869(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH XLKD1
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