Protein name:
Intercellular adhesion molecule 1 (ICAM-1) ;
Alternative:
CD:
CD54 ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Sub Unit:
Homodimer. Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF.
Function:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
APALPRLPAL | LALLGALLPG | LGGAQTSVDP | AEAIILRGGS | VQVNCSTSCN |
100:
QTSIFGLETL | LTKTEVTSGD | NWVLFELTDV | QEDSKLICFS | NCHDETMAPI |
150:
DLTVYWFPER | VELAPLPRWQ | PVGENLTMTC | QVAGGAPRTN | LTVVLLRGEE |
200:
ELSRQPAVGE | PAEVTFTVAV | GREDHLANFS | CRTDLDLRHR | GLGLFQNSSA |
250:
PRQLQTFVLP | ETPPRLATPP | IVEVGTQWSV | DCTMDGVFPA | SEAQVHLALA |
300:
EERLHSTVLY | KKDSLLATAN | VKANPEDEGT | QQLWCEVTLG | DENRRWQENV |
350:
TFYSFPAPNL | TLSEPEVSEW | TTVTVECEAP | AGVVVSLSGL | PSGLAVPRAQ |
400:
FQLNASAADN | RRSFSCSAAL | EVAGHMLQKN | QTRELHVLYG | PRLDQRDCPG |
450:
NWTWEEGFHQ | TLKCQAWGNP | VPELKCHRKG | DDALLPIGDL | RPVKREVAGT |
500:
YLCQARSPRG | EITREVVINV | IYHQNNILII | ILVTTIVILG | TVSVAAYLYN |
528:
RQRKIQKYKL | QKAQEAAAMK | LNTPATPP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Dog
Human
Bovine
Polyclonal Antibody for Dog ICAM-1
Polyclonal Antibody for Dog ICAM-1
Polyclonal Antibody for Dog ICAM-1
Polyclonal Antibody for Dog ICAM-1
Polyclonal Antibody for Dog ICAM-1
Monoclonal Antibody for Dog ICAM-1
Monoclonal Antibody for Dog ICAM-1
Monoclonal Antibody for Dog ICAM-1
Monoclonal Antibody for Dog ICAM-1
Monoclonal Antibody for Dog ICAM-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 184-413
tissue :
Cardiac myocyte .