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Index > Protein center > Il6st(Gene name) > Mouse
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  • Il6st (Gene name),
  • Interleukin-6 receptor subunit beta (Protein name ),  IL6RB_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Il6st;
    Protein name:
    Interleukin-6 receptor subunit beta(IL-6 receptor subunit beta;IL-6R subunit beta;IL-6R-beta;IL-6RB);
    Alternative:
    Membrane glycoprotein 130(gp130);Interleukin-6 signal transducer;Oncostatin-M receptor subunit alpha;
    CD:
    CD130;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of a hexamer of two molecules each of IL6, IL6R and IL6ST (By similarity). Forms heterodimers composed of LIPR and IL6ST (type I OSM receptor). Also forms heterodimers composed of OSMR and IL6ST (type II OSM receptor). Interacts with INPP5D/SHIP1.
    Function:
    Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    917
    Sequence:
    50:
    MSAPRIWLAQ | ALLFFLTTES | IGQLLEPCGY | IYPEFPVVQR | GSNFTAICVL | 
    100:
    KEACLQHYYV | NASYIVWKTN | HAAVPREQVT | VINRTTSSVT | FTDVVLPSVQ | 
    150:
    LTCNILSFGQ | IEQNVYGVTM | LSGFPPDKPT | NLTCIVNEGK | NMLCQWDPGR | 
    200:
    ETYLETNYTL | KSEWATEKFP | DCQSKHGTSC | MVSYMPTYYV | NIEVWVEAEN | 
    250:
    ALGKVSSESI | NFDPVDKVKP | TPPYNLSVTN | SEELSSILKL | SWVSSGLGGL | 
    300:
    LDLKSDIQYR | TKDASTWIQV | PLEDTMSPRT | SFTVQDLKPF | TEYVFRIRSI | 
    350:
    KDSGKGYWSD | WSEEASGTTY | EDRPSRPPSF | WYKTNPSHGQ | EYRSVRLIWK | 
    400:
    ALPLSEANGK | ILDYEVILTQ | SKSVSQTYTV | TGTELTVNLT | NDRYVASLAA | 
    450:
    RNKVGKSAAA | VLTIPSPHVT | AAYSVVNLKA | FPKDNLLWVE | WTPPPKPVSK | 
    500:
    YILEWCVLSE | NAPCVEDWQQ | EDATVNRTHL | RGRLLESKCY | QITVTPVFAT | 
    550:
    GPGGSESLKA | YLKQAAPARG | PTVRTKKVGK | NEAVLAWDQI | PVDDQNGFIR | 
    600:
    NYSISYRTSV | GKEMVVHVDS | SHTEYTLSSL | SSDTLYMVRM | AAYTDEGGKD | 
    650:
    GPEFTFTTPK | FAQGEIEAIV | VPVCLAFLLT | TLLGVLFCFN | KRDLIKKHIW | 
    700:
    PNVPDPSKSH | IAQWSPHTPP | RHNFNSKDQM | YSDGNFTDVS | VVEIEANNKK | 
    750:
    PCPDDLKSVD | LFKKEKVSTE | GHSSGIGGSS | CMSSSRPSIS | SNEENESAQS | 
    800:
    TASTVEYSTV | VHSGYRHQVP | SVQVFSRSES | TQPLLDSEER | PEDLQLVDSV | 
    850:
    DGGDEILPRQ | PYFKQNCSQP | EACPEISHFE | RSNQVLSGNE | EDFVRLKQQQ | 
    900:
    VSDHISQPYG | SEQRRLFQEG | STADALGTGA | DGQMERFESV | GMETTIDEEI | 
    917:
    PKSYLPQTVR | QGGYMPQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    E0046h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    E0046m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    E0046r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    U0046r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    U0046m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse IL-6 receptor subunit beta
    Cat.:
    U0046h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Mouse IL-6 receptor subunit beta
    Cat.:
    P0046Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-6 receptor subunit beta
    Cat.:
    P0046Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse IL-6 receptor subunit beta
    Cat.:
    P0046Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse IL-6 receptor subunit beta
    Monoclonal Antibody for Mouse IL-6 receptor subunit beta
    Monoclonal Antibody for Mouse IL-6 receptor subunit beta
    Protein for Mouse IL-6 receptor subunit beta
    Protein for Mouse IL-6 receptor subunit beta
    Protein for Mouse IL-6 receptor subunit beta

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning of a murine IL-6 receptor-associated signal transducer, gp130, and its regulated expression in vivo."
      Saito M. , Yoshida K. , Hibi M. , Taga T. , Kishimoto T.
      J. Immunol.148:4066-4071(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: ICR.
      tissue: Macrophage.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the OSM receptor beta subunit."
      Tanaka M. , Hara T. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Miyajima A.
      Blood93:804-815(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    5. 5.
      "s-SHIP associates with receptor complexes essential for pluripotent stem cell growth and survival."
      Desponts C. , Ninos J.M. , Kerr W.G.
      Stem Cells Dev.15:641-646(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH INPP5D
    6. 6.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-225
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