JAK1 ELISA Kit for Human(Homo sapiens) | EIAab.comJAK1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > JAK1(Gene name) > Human

JAK1 (Gene name),

Tyrosine-protein kinase JAK1 (Protein name ), JAK1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

JAK1(JAK1A;JAK1B);

Protein name:

Tyrosine-protein kinase JAK1;

Alternative:

Janus kinase 1(JAK-1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with IL31RA, IFNAR2, JAKMIP1 and SHB.

Function:

Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.

Subcellular Location:

Endomembrane system Peripheral membrane protein Wholly intracellular, possibly membrane associated.

Protein Attributes:

Sequence length:

1154

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1154:

ALLK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000343204

UniGene:

Hs.207538

KEGG:

hsa:3716

MIM:

147795

Pfam:

PF07714

String:

P23458

SMR:

P23458

Uniprot:

P23458

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ELISA Kit for Human Tyrosine-protein kinase JAK1

Cat.:

E9729h

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96T

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ELISA Kit for Human Tyrosine-protein kinase JAK1

Cat.:

E9729m

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Manual:

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96T

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CLIA Kit for Human Tyrosine-protein kinase JAK1

Cat.:

U9729h

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Manual:

Looking for manual.

MSDS:

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96T

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CLIA Kit for Human Tyrosine-protein kinase JAK1

Cat.:

U9729m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Tyrosine-protein kinase JAK1

Cat.:

P9729Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tyrosine-protein kinase JAK1

Cat.:

P9729Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Monoclonal Antibody for Human Tyrosine-protein kinase JAK1

Protein for Human Tyrosine-protein kinase JAK1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase."
Wilks A.F. , Harpur A.G. , Kurban R.R. , Ralph S.J. , Zuercher G. , Ziemiecki A.
Mol. Cell. Biol.11:2057-2065(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
6.

"A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes."
Lee S.-T. , Strunk K.M. , Spritz R.A.
Oncogene8:3403-3410(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1005-1062
7.

"Receptor tyrosine kinases expressed in metastatic colon cancer."
Craven R.J. , Xu L.H. , Weiner T.M. , Fridell Y.-W. , Dent G.A. , Srivastava S. , Varnum B. , Liu E.T. , Cance W.G.
Int. J. Cancer60:791-797(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1008-1062;TISSUE SPECIFICITY
tissue: Colon tumor.
8.

"Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor."
Novick D. , Cohen B. , Tal N. , Rubinstein M.
J. Leukoc. Biol.57:712-718(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IFNAR2
9.

"IL-2 receptor signaling through the Shb adapter protein in T and NK cells."
Lindholm C.K.
Biochem. Biophys. Res. Commun.296:929-936(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SHB
10.

"The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3."
Simoncic P.D. , Lee-Loy A. , Barber D.L. , Tremblay M.L. , McGlade C.J.
Curr. Biol.12:446-453(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN CYTOKINE SIGNALING;PHOSPHORYLATION AT TYR-1034 AND TYR-1035;DEPHOSPHORYLATION AT TYR-1034 AND TYR-1035 BY PTPN2
11.

"Characterization of the signaling capacities of the novel gp130-like cytokine receptor."
Dreuw A. , Radtke S. , Pflanz S. , Lippok B.E. , Heinrich P.C. , Hermanns H.M.
J. Biol. Chem.279:36112-36120(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL31RA
12.

"Jamip1 (marlin-1) defines a family of proteins interacting with Janus kinases and microtubules."
Steindler C. , Li Z. , Algarte M. , Alcover A. , Libri V. , Ragimbeau J. , Pellegrini S.
J. Biol. Chem.279:43168-43177(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JAKMIP1
13.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-3 AND SER-228;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains."
Williams N.K. , Bamert R.S. , Patel O. , Wang C. , Walden P.M. , Wilks A.F. , Fantino E. , Rossjohn J. , Lucet I.S.
J. Mol. Biol.387:219-232(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 865-1154 IN COMPLEXES WITH SYNTHETIC INHIBITORS CMP6 AND CP-690,550
16.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LYS-973

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