Lgals3 ELISA Kit for Mouse(Mus musculus) | EIAab.comLgals3 ELISA Kit for Mouse(Mus musculus)

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Lgals3 (Gene name),

Galectin-3 (Protein name ), LEG3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Lgals3;

Protein name:

Galectin-3(Gal-3);

Alternative:

Carbohydrate-binding protein 35(CBP 35);35 kDa lectin;IgE-binding protein;Galactose-specific lectin 3;Laminin-binding protein;L-34 galactoside-binding lectin;Mac-2 antigen;Lectin L-29;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Probably forms homo- or heterodimers. Interacts with DMBT1 (By similarity). Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA.

Function:

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Subcellular Location:

Cytoplasm Nucleus Secreted Secreted by a non-classical secretory pathway and associates with the cell surface.

Protein Attributes:

Sequence length:

264

Sequence:

50:

100:

150:

200:

250:

264:

SGDITLTSAN | HAMI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P16110

Pfam:

PF00337

UniGene:

Mm.248615

STRING:

10090.ENSMUSP00000022388

String:

P16110

Uniprot:

P16110

FOR

ELISA Kit for Mouse Gal-3

Cat.:

E0497m

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96T

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ELISA Kit for Mouse Gal-3

Cat.:

E0497h

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96T

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ELISA Kit for Mouse Gal-3

Cat.:

E0497r

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ELISA Kit for Mouse Gal-3

Cat.:

E0497d

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96T

ELISA Kit for Mouse Gal-3

MSDS:

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CLIA Kit for Mouse Gal-3

Cat.:

U0497d

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96T

CLIA Kit for Mouse Gal-3

Cat.:

U0497r

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96T

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CLIA Kit for Mouse Gal-3

MSDS:

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CLIA Kit for Mouse Gal-3

Cat.:

U0497h

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96T

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CLIA Kit for Mouse Gal-3

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U0497m

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Polyclonal Antibody for Mouse Gal-3

Cat.:

P0497Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Gal-3

Cat.:

P0497Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Gal-3

Cat.:

P0497Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse Gal-3

Monoclonal Antibody for Mouse Gal-3

Protein for Mouse Gal-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The Mac-2 antigen is a galactose-specific lectin that binds IgE."
Cherayil B.J. , Weiner S.J. , Pillai S.
J. Exp. Med.170:1959-1972(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: DBA/2J.
tissue: Macrophage.
2.

"Carbohydrate binding protein 35. Complementary DNA sequence reveals homology with proteins of the heterogeneous nuclear RNP."
Jia S. , Wang J.L.
J. Biol. Chem.263:6009-6011(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Identification of the metastasis-associated, galactoside-binding lectin as a chimeric gene product with homology to an IgE-binding protein."
Raz A. , Pazerini G. , Carmi P.
Cancer Res.49:3489-3493(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The major non-integrin laminin binding protein of macrophages is identical to carbohydrate binding protein 35 (Mac-2)."
Woo H.-J. , Shaw L.M. , Messier J.M. , Mercurio A.M.
J. Biol. Chem.265:7097-7099(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 159-163; 166-175 AND 214-226
5.

Lubec G. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 184-190 AND 201-213;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
6.

"Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186."
Woo H.-J. , Lotz M.M. , Jung J.U. , Mercurio A.M.
J. Biol. Chem.266:18419-18422(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
7.

"Interaction of a novel cysteine and histidine-rich cytoplasmic protein with galectin-3 in a carbohydrate-independent manner galectin 3."
Menon R.P. , Strom M. , Hughes R.C.
FEBS Lett.470:227-231(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CYHR1
8.

"Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling."
Liu L. , Sakai T. , Sano N. , Fukui K.
Biochem. J.380:31-41(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UACA
9.

"NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin."
Fukushi J. , Makagiansar I.T. , Stallcup W.B.
Mol. Biol. Cell15:3580-3590(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH ITGB1; ITGA3 AND CSPG4;FUNCTION
10.

"Transport of galectin-3 between the nucleus and cytoplasm. II. Identification of the signal for nuclear export."
Li S.Y. , Davidson P.J. , Lin N.Y. , Patterson R.J. , Wang J.L. , Arnoys E.J.
Glycobiology16:612-622(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;NUCLEAR EXPORT SIGNAL

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