Protein name:
Galectin-3 (Gal-3) ;
Alternative:
Carbohydrate-binding protein 35 (CBP 35) ;35 kDa lectin ;IgE-binding protein ;Galactose-specific lectin 3 ;Lectin L-29 ;Laminin-binding protein ;Mac-2 antigen ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Probably forms homo- or heterodimers. Forms a complex with the ITGA3, ITGB1 and CSPG4. Interacts with LGALS3BP, LYPD3, CYHR1 and UACA (By similarity). Interacts with DMBT1.
Function:
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells (By similarity). Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Subcellular Location:
Cytoplasm
Nucleus
Secreted
Secreted by a non-classical secretory pathway and associates with the cell surface.
Protein Attributes:
50:
MADGFSLNDA | LAGSGNPNPQ | GWPGAWGNQP | GAGGYPGASY | PGAYPGQAPP |
100:
GGYPGQAPPS | AYPGPTGPSA | YPGPTAPGAY | PGPTAPGAFP | GQPGGPGAYP |
150:
SAPGAYPSAP | GAYPATGPFG | APTGPLTVPY | DMPLPGGVMP | RMLITIIGTV |
200:
KPNANSITLN | FKKGNDIAFH | FNPRFNENNR | RVIVCNTKQD | NNWGREERQS |
250:
AFPFESGKPF | KIQVLVEADH | FKVAVNDVHL | LQYNHRMKNL | REISQLGIIG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
Dog
Rabbit
Polyclonal Antibody for Rat Gal-3
Polyclonal Antibody for Rat Gal-3
Polyclonal Antibody for Rat Gal-3
Polyclonal Antibody for Rat Gal-3
Polyclonal Antibody for Rat Gal-3
Monoclonal Antibody for Rat Gal-3
Monoclonal Antibody for Rat Gal-3
Monoclonal Antibody for Rat Gal-3
Monoclonal Antibody for Rat Gal-3
Monoclonal Antibody for Rat Gal-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 120-145
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 125-262
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 164-174 AND 223-236;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Spinal cord .
6.
"Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase."
Herrmann J.
,
Turck C.W.
,
Atchison R.E.
,
Huflejt M.E.
,
Poulter L.
,
Gitt M.A.
,
Burlingame A.L.
,
Barondes S.H.
,
Leffler H.
J. Biol. Chem.268:26704-26711(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PARTIAL PROTEIN SEQUENCE;ACETYLATION AT ALA-2
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH DMBT1;FUNCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LYPD3