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Index > Protein center > Lifr(Gene name) > Mouse
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  • Lifr (Gene name),
  • Leukemia inhibitory factor receptor (Protein name ),  LIFR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Lifr;
    Protein name:
    Leukemia inhibitory factor receptor(LIF receptor;LIF-R);
    Alternative:
    D-factor/LIF receptor;
    CD:
    CD118;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer composed of LIFR and IL6ST. The heterodimer formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR.
    Function:
    Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    1092
    Sequence:
    50:
    MAAYSWWRQP | SWMVDNKRSR | MTPNLPWLLS | ALTLLHLTMH | ANGLKRGVQD | 
    100:
    LKCTTNNMRV | WDCTWPAPLG | VSPGTVKDIC | IKDRFHSCHP | LETTNVKIPA | 
    150:
    LSPGDHEVTI | NYLNGFQSKF | TLNEKDVSLI | PETPEILDLS | ADFFTSSLLL | 
    200:
    KWNDRGSALP | HPSNATWEIK | VLQNPRTEPV | ALVLLNTMLS | GKDTVQHWNW | 
    250:
    TSDLPLQCAT | HSVSIRWHID | SPHFSGYKEW | SDWSPLKNIS | WIRNTETNVF | 
    300:
    PQDKVVLAGS | NMTICCMSPT | KVLSGQIGNT | LRPLIHLYGQ | TVAIHILNIP | 
    350:
    VSENSGTNII | FITDDDVYGT | VVFAGYPPDV | PQKLSCETHD | LKEIICSWNP | 
    400:
    GRITGLVGPR | NTEYTLFESI | SGKSAVFHRI | EGLTNETYRL | GVQMHPGQEI | 
    450:
    HNFTLTGRNP | LGQAQSAVVI | NVTERVAPHD | PTSLKVKDIN | STVVTFSWYL | 
    500:
    PGNFTKINLL | CQIEICKANS | KKEVRNATIR | GAEDSTYHVA | VDKLNPYTAY | 
    550:
    TFRVRCSSKT | FWKWSRWSDE | KRHLTTEATP | SKGPDTWREW | SSDGKNLIVY | 
    600:
    WKPLPINEAN | GKILSYNVSC | SLNEETQSVL | EIFDPQHRAE | IQLSKNDYII | 
    650:
    SVVARNSAGS | SPPSKIASME | IPNDDITVEQ | AVGLGNRIFL | TWRHDPNMTC | 
    700:
    DYVIKWCNSS | RSEPCLLDWR | KVPSNSTETV | IESDQFQPGV | RYNFYLYGCT | 
    750:
    NQGYQLLRSI | IGYVEELAPI | VAPNFTVEDT | SADSILVKWD | DIPVEELRGF | 
    800:
    LRGYLFYFQK | GERDTPKTRS | LEPHHSDIKL | KNITDISQKT | LRIADLQGKT | 
    850:
    SYHLVLRAYT | HGGLGPEKSM | FVVTKENSVG | LIIAILIPVA | VAVIVGVVTS | 
    900:
    ILCYRKREWI | KETFYPDIPN | PENCKALQFQ | KSVCEGSNAL | KTLEMNPCTP | 
    950:
    NNVEVLESRS | IVPKIEDTEI | ISPVAERPGE | RSEVDPENHV | VVSYCPPIIE | 
    1000:
    EEITNPAADE | VGGASQVVYI | DVQSMYQPQA | KAEEEQDVDP | VVVAGYKPQM | 
    1050:
    RLPISPAVED | TAAEDEEGKT | AGYRPQANVN | TWNLVSPDSP | RSTDSNNEVV | 
    1092:
    SFGSPCSINS | RQFLIPPKDE | DSPKSNGGGW | SFTNFFQNKP | ND
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse LIF receptor
    Cat.:
    E0561h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse LIF receptor
    Cat.:
    E0561d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse LIF receptor
    Cat.:
    E0561r
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    Packing:
    96T
    ELISA Kit for Mouse LIF receptor
    Cat.:
    E0561m
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    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LIF receptor
    Cat.:
    U0561d
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LIF receptor
    Cat.:
    U0561r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LIF receptor
    Cat.:
    U0561m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse LIF receptor
    Cat.:
    U0561h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse LIF receptor
    Cat.:
    P0561Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LIF receptor
    Cat.:
    P0561Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse LIF receptor
    Polyclonal Antibody for Mouse LIF receptor
    Cat.:
    P0561Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse LIF receptor
    Monoclonal Antibody for Mouse LIF receptor
    Monoclonal Antibody for Mouse LIF receptor
    Monoclonal Antibody for Mouse LIF receptor
    Protein for Mouse LIF receptor
    Protein for Mouse LIF receptor
    Protein for Mouse LIF receptor
    Protein for Mouse LIF receptor

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130."
      Gearing D.P. , Thut C.J. , Vanden Bos T. , Gimpel S.D. , Delaney P.B. , King J. , Price V. , Cosman D. , Beckmann M.P.
      EMBO J.10:2839-2848(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Pregnancy associated increase in mRNA for soluble D-factor/LIF receptor in mouse liver."
      Tomida M. , Yamamoto-Yamaguchi Y. , Hozumi M.
      FEBS Lett.334:193-197(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      strain: ICR.
      tissue: Liver.
    3. 3.
      "Three different cDNAs encoding mouse D-factor/LIF receptor."
      Tomida M. , Yamamoto-Yamaguchi Y. , Hozumi M.
      J. Biochem.115:557-562(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: FVB/N.
      tissue: Liver.
    5. 5.
      "Proteome-wide characterization of N-glycosylation events by diagonal chromatography."
      Ghesquiere B. , Van Damme J. , Martens L. , Vandekerckhove J. , Gevaert K.
      J. Proteome Res.5:2438-2447(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-385; ASN-402 AND ASN-675
      strain: C57BL/6.
      tissue: Plasma.
    6. 6.
      "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
      Bernhard O.K. , Kapp E.A. , Simpson R.J.
      J. Proteome Res.6:987-995(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-385 AND ASN-658
      strain: C57BL/6.
      tissue: Plasma.
    7. 7.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-385
    8. 8.
      "An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor."
      Huyton T. , Zhang J.G. , Luo C.S. , Lou M.Z. , Hilton D.J. , Nicola N.A. , Garrett T.P.
      Proc. Natl. Acad. Sci. U.S.A.104:12737-12742(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (4.0 ANGSTROMS) OF 49-529 IN COMPLEX WITH HUMAN LIF;DISULFIDE BOND;GLYCOSYLATION AT ASN-164; ASN-199; ASN-238; ASN-261; ASN-385; ASN-402; ASN-421; ASN-440 AND ASN-453
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