Gene name:
LNX1 (UNQ574/PRO1136;UNQ574/PRO1136;LNX;PDZRN2) ;
Protein name:
E3 ubiquitin-protein ligase LNX ;
Alternative:
Numb-binding protein 1 ;Ligand of Numb-protein X 1 ;PDZ domain-containing RING finger protein 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with the phosphotyrosine interaction domain of all isoforms of NUMB (By similarity). Interacts with the Coxsackievirus and adenovirus receptor CXADR. Interacts with endogenous retrovirus K protein Np9. IGSF5/JAM4 interacts with isoform 2 through the second PDZ domain, other isoforms may also interact with IGSF5/JAM4.
Function:
Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MNQPESANDP | EPLCAVCGQA | HSLEENHFYS | YPEEVDDDLI | CHICLQALLD |
100:
PLDTPCGHTY | CTLCLTNFLV | EKDFCPMDRK | PLVLQHCKKS | SILVNKLLNK |
150:
LLVTCPFREH | CTQVLQRCDL | EHHFQTSCKG | ASHYGLTKDR | KRRSQDGCPD |
200:
GCASLTATAP | SPEVSAAATI | SLMTDEPGLD | NPAYVSSAED | GQPAISPVDS |
250:
GRSNRTRARP | FERSTIRSRS | FKKINRALSV | LRRTKSGSAV | ANHADQGREN |
300:
SENTTAPEVF | PRLYHLIPDG | EITSIKINRV | DPSESLSIRL | VGGSETPLVH |
350:
IIIQHIYRDG | VIARDGRLLP | GDIILKVNGM | DISNVPHNYA | VRLLRQPCQV |
400:
LWLTVMREQK | FRSRNNGQAP | DAYRPRDDSF | HVILNKSSPE | EQLGIKLVRK |
450:
VDEPGVFIFN | VLDGGVAYRH | GQLEENDRVL | AINGHDLRYG | SPESAAHLIQ |
500:
ASERRVHLVV | SRQVRQRSPD | IFQEAGWNSN | GSWSPGPGER | SNTPKPLHPT |
550:
ITCHEKVVNI | QKDPGESLGM | TVAGGASHRE | WDLPIYVISV | EPGGVISRDG |
600:
RIKTGDILLN | VDGVELTEVS | RSEAVALLKR | TSSSIVLKAL | EVKEYEPQED |
650:
CSSPAALDSN | HNMAPPSDWS | PSWVMWLELP | RCLYNCKDIV | LRRNTAGSLG |
700:
FCIVGGYEEY | NGNKPFFIKS | IVEGTPAYND | GRIRCGDILL | AVNGRSTSGM |
728:
IHACLARLLK | ELKGRITLTI | VSWPGTFL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human E3 ubiquitin-protein ligase LNX
ELISA Kit for Human E3 ubiquitin-protein ligase LNX
CLIA Kit for Human E3 ubiquitin-protein ligase LNX
CLIA Kit for Human E3 ubiquitin-protein ligase LNX
Polyclonal Antibody for Human E3 ubiquitin-protein ligase LNX
Polyclonal Antibody for Human E3 ubiquitin-protein ligase LNX
Monoclonal Antibody for Human E3 ubiquitin-protein ligase LNX
Monoclonal Antibody for Human E3 ubiquitin-protein ligase LNX
Protein for Human E3 ubiquitin-protein ligase LNX
Protein for Human E3 ubiquitin-protein ligase LNX
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
tissue :
Fetal brain .
2.
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F.
,
Gurney A.L.
,
Abaya E.
,
Baker K.
,
Baldwin D.T.
,
Brush J.
,
Chen J.
,
Chow B.
,
Chui C.
,
Crowley C.
,
Currell B.
,
Deuel B.
,
Dowd P.
,
Eaton D.
,
Foster J.S.
,
Grimaldi C.
,
Gu Q.
,
Hass P.E.
,
Heldens S.
,
Huang A.
,
Kim H.S.
,
Klimowski L.
,
Jin Y.
,
Johnson S.
,
Lee J.
,
Lewis L.
,
Liao D.
,
Mark M.R.
,
Robbie E.
,
Sanchez C.
,
Schoenfeld J.
,
Seshagiri S.
,
Simmons L.
,
Singh J.
,
Smith V.
,
Stinson J.
,
Vagts A.
,
Vandlen R.L.
,
Watanabe C.
,
Wieand D.
,
Woods K.
,
Xie M.-H.
,
Yansura D.G.
,
Yi S.
,
Yu G.
,
Yuan J.
,
Zhang M.
,
Zhang Z.
,
Goddard A.D.
,
Wood W.I.
,
Godowski P.J.
,
Gray A.M.
more...
Genome Res.13:2265-2270(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
3.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Prostate .
4.
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W.
,
Graves T.A.
,
Fulton R.S.
,
Fulton L.A.
,
Pepin K.H.
,
Minx P.
,
Wagner-McPherson C.
,
Layman D.
,
Wylie K.
,
Sekhon M.
,
Becker M.C.
,
Fewell G.A.
,
Delehaunty K.D.
,
Miner T.L.
,
Nash W.E.
,
Kremitzki C.
,
Oddy L.
,
Du H.
,
Sun H.
,
Bradshaw-Cordum H.
,
Ali J.
,
Carter J.
,
Cordes M.
,
Harris A.
,
Isak A.
,
van Brunt A.
,
Nguyen C.
,
Du F.
,
Courtney L.
,
Kalicki J.
,
Ozersky P.
,
Abbott S.
,
Armstrong J.
,
Belter E.A.
,
Caruso L.
,
Cedroni M.
,
Cotton M.
,
Davidson T.
,
Desai A.
,
Elliott G.
,
Erb T.
,
Fronick C.
,
Gaige T.
,
Haakenson W.
,
Haglund K.
,
Holmes A.
,
Harkins R.
,
Kim K.
,
Kruchowski S.S.
,
Strong C.M.
,
Grewal N.
,
Goyea E.
,
Hou S.
,
Levy A.
,
Martinka S.
,
Mead K.
,
McLellan M.D.
,
Meyer R.
,
Randall-Maher J.
,
Tomlinson C.
,
Dauphin-Kohlberg S.
,
Kozlowicz-Reilly A.
,
Shah N.
,
Swearengen-Shahid S.
,
Snider J.
,
Strong J.T.
,
Thompson J.
,
Yoakum M.
,
Leonard S.
,
Pearman C.
,
Trani L.
,
Radionenko M.
,
Waligorski J.E.
,
Wang C.
,
Rock S.M.
,
Tin-Wollam A.-M.
,
Maupin R.
,
Latreille P.
,
Wendl M.C.
,
Yang S.-P.
,
Pohl C.
,
Wallis J.W.
,
Spieth J.
,
Bieri T.A.
,
Berkowicz N.
,
Nelson J.O.
,
Osborne J.
,
Ding L.
,
Meyer R.
,
Sabo A.
,
Shotland Y.
,
Sinha P.
,
Wohldmann P.E.
,
Cook L.L.
,
Hickenbotham M.T.
,
Eldred J.
,
Williams D.
,
Jones T.A.
,
She X.
,
Ciccarelli F.D.
,
Izaurralde E.
,
Taylor J.
,
Schmutz J.
,
Myers R.M.
,
Cox D.R.
,
Huang X.
,
McPherson J.D.
,
Mardis E.R.
,
Clifton S.W.
,
Warren W.C.
,
Chinwalla A.T.
,
Eddy S.R.
,
Marra M.A.
,
Ovcharenko I.
,
Furey T.S.
,
Miller W.
,
Eichler E.E.
,
Bork P.
,
Suyama M.
,
Torrents D.
,
Waterston R.H.
,
Wilson R.K.
more...
Nature434:724-731(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue :
Brain .
tissue :
Placenta .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CXADR
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NP9
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAGEB18 AND MAGEF1
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]