Gene name:
Med16 (Thrap5) ;
Protein name:
Mediator of RNA polymerase II transcription subunit 16 ;
Alternative:
Thyroid hormone receptor-associated protein 5 ;Mediator complex subunit 16 ;Vitamin D3 receptor-interacting protein complex 92 kDa component (DRIP92) ;Thyroid hormone receptor-associated protein complex 95 kDa component (Trap95) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MDLAYVCEWE | KWAKSTYCPS | LPLACAWSCR | NLIAFTTDLR | NDDQDLTHMI |
100:
HILDTEHPWE | VHSVSSGHSE | AITCLEWDQS | GSRLLSADAD | GQIKCWSMAD |
150:
HLANSWESSV | GSQVEGDPIV | ALSWLHNGVK | LALHVEKSGA | SSFGEKFSRV |
200:
KFSPSLTLFG | GKPMEGWIAV | TVSGLVTVSL | LKPSGQVLTS | TESLCRLRGR |
250:
VALADIAFTG | GGNIVVAAAD | GSSASPVKFY | KVCVSVVSEK | CRIDTEILPS |
300:
LFMRCTTDPN | RKDRFPAITH | LKFLARDMSE | QVLLCASSQT | SSLVECWSLR |
350:
KEGLPVNNIF | QQISPVVGDK | QPMILKWRIL | SATNDLDRVS | AVALPKLPIS |
400:
LTNTDLKVAS | DTQFYPGLGL | ALAFQDGSVH | MVHRLSLQTM | AVFYSSAPRS |
450:
LDEPALKRPR | TTCPAVHFKA | MQLSWTSLAL | VGIDNHGKLS | MLRISPSLGH |
500:
PLEPKLALQH | LLFLLEYCMV | TGYDWWDILL | HVQPGMVQSL | VERLHEEYTR |
550:
QKPALQQVLS | TRILAMKASL | CKLSPCTVAR | VCDYHTKLFL | MAITSTLKSL |
600:
LRPHFLNTPD | KSPGDRLAEI | CAKITDVDID | KVMINLKTEE | FVLDMNTLQA |
650:
LQQLLQWVGD | FVLYLLVSLP | NQGSPLRPGH | SFLRDGTSLG | MLRELMVVIR |
700:
IWGLLKPSCL | PVYTATSDTQ | DSMSLLFRLL | TKLWICCRDE | GAASEPDEGL |
750:
VDECCLLPSQ | LLVPNLDWLP | ASDGLVSRLQ | PKQPLRLRFG | RAPTLPSSTS |
800:
TLQLDGLTRA | PGQPKIDHLR | RLHLGAYPTE | ECKACTRCGC | VTMLKSPNKT |
828:
TAVTQWEQRW | IKNCLCGGLW | RRVPLSCS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Mediator of RNA polymerase II transcription subunit 16
ELISA Kit for Mouse Mediator of RNA polymerase II transcription subunit 16
CLIA Kit for Mouse Mediator of RNA polymerase II transcription subunit 16
CLIA Kit for Mouse Mediator of RNA polymerase II transcription subunit 16
Polyclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 16
Polyclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 16
Monoclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 16
Monoclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 16
Protein for Mouse Mediator of RNA polymerase II transcription subunit 16
Protein for Mouse Mediator of RNA polymerase II transcription subunit 16
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .