Gene name:
MMP17 (MT4MMP) ;
Protein name:
Matrix metalloproteinase-17 (MMP-17) ;
Alternative:
Membrane-type-4 matrix metalloproteinase (MT4-MMP;MT4MMP) ;Membrane-type matrix metalloproteinase 4 (MT-MMP 4;MTMMP4) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Subcellular Location:
Isoform Long
Cell membrane
Lipid-anchor
GPI-anchor
Extracellular side
Secreted
extracellular space
extracellular matrix
Protein Attributes:
50:
MRRRAARGPG | PPPPGPGLSR | LPLPLLLLLA | LGTRGGCAAP | APAPRAEDLS |
100:
LGVEWLSRFG | YLPPADPTTG | QLQTQEELSK | AITAMQQFGG | LEATGILDEA |
150:
TLALMKTPRC | SLPDLPVLTQ | ARRRRQAPAP | TKWNKRNLSW | RVRTFPRDSP |
200:
LGHDTVRALM | YYALKVWSDI | APLNFHEVAG | SAADIQIDFS | KADHNDGYPF |
250:
DGPGGTVAHA | FFPGHHHTAG | DTHFDDDEAW | TFRSSDAHGM | DLFAVAVHEF |
300:
GHAIGLSHVA | AAHSIMRPYY | QGPVGDPLRY | GLPYEDKVRV | WQLYGVRESV |
350:
SPTAQPEEPP | LLPEPPDNRS | SAPPRKDVPH | RCSTHFDAVA | QIRGEAFFFK |
400:
GKYFWRLTRD | RHLVSLQPAQ | MHRFWRGLPL | HLDSVDAVYE | RTSDHKIVFF |
450:
KGDRYWVFKD | NNVEEGYPRP | VSDFSLPPGG | IDAAFSWAHN | DRTYFFKDQL |
500:
YWRYDDHTRH | MDPGYPAQSP | LWRGVPSTLD | DAMRWSDGAS | YFFRGQEYWK |
550:
VLDGELEVAP | GYPQSTARDW | LVCGDSQADG | SVAAGVDAAE | GPRAPPGQHD |
600:
QSRSEDGYEV | CSCTSGASSP | PGAPGPLVAA | TMLLLLPPLS | PGALWTAAQA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human MMP-17
ELISA Kit for Human MMP-17
CLIA Kit for Human MMP-17
CLIA Kit for Human MMP-17
Polyclonal Antibody for Human MMP-17
Polyclonal Antibody for Human MMP-17
Monoclonal Antibody for Human MMP-17
Monoclonal Antibody for Human MMP-17
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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