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Index > Protein center > Myo18a(Gene name) > Mouse
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  • Myo18a (Gene name),
  • Myosin-XVIIIa (Protein name ),  MY18A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Myo18a(Myspdz);
    Protein name:
    Myosin-XVIIIa;
    Alternative:
    Myosin containing a PDZ domain;Molecule associated with JAK3 N-terminus(MAJN);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with JAK3 and actin.
    Function:
    May be involved in the maintenance of the stromal cell architecture required for cell to cell contact. Isoform 1 may be related to adherence and/or some other functions of mature macrophages.
    Subcellular Location:
    Isoform 2 Cytoplasm Lacks the PDZ domain. Diffusely localized in the cytoplasm.
    Protein Attributes:
    Sequence length:
    2050
    Sequence:
    50:
    MFNLMKKDKD | KDGGRKEKKE | KKEKKERMSA | AELRSLEEMS | MRRGFFNLNR | 
    100:
    SSKRESKTRL | EISNPIPIKV | ASGSDLHLTD | IDSDSNRGSI | ILDSGHLSTA | 
    150:
    SSSDDLKGEE | GSFRGSVLQR | AAKFGSLAKQ | NSQMIVKRFS | FSQRSRDESA | 
    200:
    SETSTPSEHS | AAPSPQVEVR | TLEGQLMQHP | GLGIPRPGPR | SRVPELVTKR | 
    250:
    FPADLRLPAL | VPPPPPALRE | LELQRRPTGD | FGFSLRRTTM | LDRAPEGQAY | 
    300:
    RRVVHFAEPG | AGTKDLALGL | VPGDRLVEIN | GQNVENKSRD | EIVEMIRQSG | 
    350:
    DSVRLKVQPI | PELSELSRSW | LRTGEGHRRE | PADAKTEEQI | AAEEAWYETE | 
    400:
    KVWLVHRDGF | SLASQLKSEE | LSLPEGKARV | KLDHDGAILD | VDEDDIEKAN | 
    450:
    APSCDRLEDL | ASLVYLNESS | VLHTLRQRYG | ASLLHTYAGP | SLLVLSTRGA | 
    500:
    PAVYSEKVMH | MFKGCRREDM | APHIYAVAQT | AYRAMLMSRQ | DQSIVLLGSS | 
    550:
    GSGKTTSFQH | LVQYLATIAG | TSGTKVFSVE | KWQALSTLLE | AFGNSPTIMN | 
    600:
    GSATRFSQIL | SLDFDQAGQV | ASASIQTMLL | EKLRVARRPA | SEATFNVFYY | 
    650:
    LLACGDATLR | TELHLNHLAE | NNVFGIVPLS | KPEEKQKAAQ | QFSKLQAAMK | 
    700:
    VLAISPEEQK | TCWLILASIY | HLGAAGATKE | AAEAGRKQFA | RHEWAQKAAY | 
    750:
    LLGCSLEELS | SAIFKHQLKG | GTLQRSTSFR | QGPEESGLGE | GTKLSALECL | 
    800:
    EGMASGLYSE | LFTLLISLVN | RALKSSQHSL | CSMMIVDTPG | FQNPEWGGSA | 
    850:
    RGASFEELCH | NYAQDRLQRL | FHERTFLQEL | ERYKEDNIEL | AFDDLEPVAD | 
    900:
    DSVAAVDQAS | HLVRSLAHAD | EARGLLWLLE | EEALVPGATE | DALLDRLFSY | 
    950:
    YGPQEGDKKG | QSPLLRSSKP | RHFLLGHSHG | TNWVEYNVAG | WLNYTKQNPA | 
    1000:
    TQNAPRLLQD | SQKKIISNLF | LGRAGSATVL | SGSIAGLEGG | SQLALRRATS | 
    1050:
    MRKTFTTGMA | AVKKKSLCIQ | IKLQVDALID | TIKRSKMHFV | HCFLPVAEGW | 
    1100:
    PGEPRSASSR | RVSSSSELDL | PPGDPCEAGL | LQLDVSLLRA | QLRGSRLLDA | 
    1150:
    MRMYRQGYPD | HMVFSEFRRR | FDVLAPHLTK | KHGRNYIVVD | EKRAVEELLE | 
    1200:
    SLDLEKSSCC | LGLSRVFFRA | GTLARLEEQR | DEQTSRHLTL | FQAACRGYLA | 
    1250:
    RQHFKKRKIQ | DLAIRCVQKN | IKKNKGVKDW | PWWKLFTTVR | PLIQVQLSEE | 
    1300:
    QIRNKDEEIQ | QLRSKLEKVE | KERNELRLSS | DRLETRISEL | TSELTDERNT | 
    1350:
    GESASQLLDA | ETAERLRTEK | EMKELQTQYD | ALKKQMEVME | MEVMEARLIR | 
    1400:
    AAEINGEVDD | DDAGGEWRLK | YERAVREVDF | TKKRLQQELE | DKMEVEQQSR | 
    1450:
    RQLERRLGDL | QADSDESQRA | LQQLKKKCQR | LTAELQDTKL | HLEGQQVRNH | 
    1500:
    ELEKKQRRFD | SELSQAHEET | QREKLQREKL | QREKDMLLAE | AFSLKQQMEE | 
    1550:
    KDLDIAGFTQ | KVVSLEAELQ | DISSQESKDE | ASLAKVKKQL | RDLEAKVKDQ | 
    1600:
    EEELDEQAGS | IQMLEQAKLR | LEMEMERMRQ | THSKEMESRD | EEVEEARQSC | 
    1650:
    QKKLKQMEVQ | LEEEYEDKQK | ALREKRELES | KLSTLSDQVN | QRDFESEKRL | 
    1700:
    RKDLKRTKAL | LADAQIMLDH | LKNNAPSKRE | IAQLKNQLEE | SEFTCAAAVK | 
    1750:
    ARKAMEVEME | DLHLQIDDIA | KAKTALEEQL | SRLQREKNEI | QNRLEEDQED | 
    1800:
    MNELMKKHKA | AVAQASRDMA | QMNDLQAQIE | ESNKEKQELQ | EKLQALQSQV | 
    1850:
    EFLEQSMVDK | SLVSRQEAKI | RELETRLEFE | KTQVKRLENL | ASRLKETMEK | 
    1900:
    LTEERDQRAA | AENREKEQNK | RLQRQLRDTK | EEMSELARKE | AEASRKKHEL | 
    1950:
    EMDLESLEAA | NQSLQADLKL | AFKRIGDLQA | AIEDEMESDE | NEDLINSLQD | 
    2000:
    MVTKYQKKKN | KLEGDSDVDS | ELEDRVDGVK | SWLSKNKGPS | KAPSDDGSLK | 
    2050:
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Myosin-XVIIIa
    ELISA Kit for Mouse Myosin-XVIIIa
    CLIA Kit for Mouse Myosin-XVIIIa
    CLIA Kit for Mouse Myosin-XVIIIa
    Polyclonal Antibody for Mouse Myosin-XVIIIa
    Polyclonal Antibody for Mouse Myosin-XVIIIa
    Monoclonal Antibody for Mouse Myosin-XVIIIa
    Monoclonal Antibody for Mouse Myosin-XVIIIa
    Protein for Mouse Myosin-XVIIIa
    Protein for Mouse Myosin-XVIIIa

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Isolation of a novel PDZ-containing myosin from hematopoietic supportive bone marrow stromal cell lines."
      Furusawa T. , Ikawa S. , Yanai N. , Obinata M.
      Biochem. Biophys. Res. Commun.270:67-75(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Spleen.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-873 (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Bone.
      tissue: Brain.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1032-2050 (ISOFORM 1)
      strain: FVB/N.
      tissue: Colon.
    5. 5.
      "A novel protein MAJN binds to Jak3 and inhibits apoptosis induced by IL-2 deprival."
      Ji H. , Zhai Q. , Zhu J. , Yan M. , Sun L. , Liu X. , Zheng Z.
      Biochem. Biophys. Res. Commun.270:267-271(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH JAK3
    6. 6.
      "Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A)."
      Mori K. , Furusawa T. , Okubo T. , Inoue T. , Ikawa S. , Yanai N. , Mori K.J. , Obinata M.
      J. Biochem.133:405-413(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORMS 1 AND 2);DIFFERENTIAL EXPRESSION
      tissue: Spleen.
    7. 7.
      "A novel 110 kDa form of myosin XVIIIA (MysPDZ) is tyrosine-phosphorylated after colony-stimulating factor-1 receptor signalling."
      Cross M. , Csar X.F. , Wilson N.J. , Manes G. , Addona T.A. , Marks D.C. , Whitty G.A. , Ashman K. , Hamilton J.A.
      Biochem. J.380:243-253(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;IDENTIFICATION BY MASS SPECTROMETRY
    8. 8.
      "Subcellular localization and dynamics of MysPDZ (Myo18A) in live mammalian cells."
      Mori K. , Matsuda K. , Furusawa T. , Kawata M. , Inoue T. , Obinata M.
      Biochem. Biophys. Res. Commun.326:491-498(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HOMODIMER;SUBCELLULAR LOCATION;INTERACTION WITH ACTIN
    9. 9.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-340 (ISOFORM 6);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-72; SER-83; SER-164; SER-1966; SER-1970; SER-2037 AND SER-2039;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    11. 11.
      "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
      Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
      J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2037 AND SER-2039;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    12. 12.
      "GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding."
      Dippold H.C. , Ng M.M. , Farber-Katz S.E. , Lee S.K. , Kerr M.L. , Peterman M.C. , Sim R. , Wiharto P.A. , Galbraith K.A. , Madhavarapu S. , Fuchs G.J. , Meerloo T. , Farquhar M.G. , Zhou H. , Field S.J.
      Cell139:337-351(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN GOLGI ORGANIZATION;MUTAGENESIS OF 503-GLY-LYS-504
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