Myo15a ELISA Kit for Mouse(Mus musculus) | EIAab.comMyo15a ELISA Kit for Mouse(Mus musculus)

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Myo15a (Gene name),

Myosin-XV (Protein name ), MYO15_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Myo15a(Myo15);

Protein name:

Myosin-XV;

Alternative:

Unconventional myosin-15;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with the third PDZ domain of WHRN which is necessary for localization of WHRN to stereocilium tips. Interacts with FASLG.

Function:

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Required for the arrangement of stereocilia in mature hair bundles.

Subcellular Location:

Cell projection stereocilium Cytoplasm cytoskeleton Localizes to stereocilium tips in cochlear and vestibular hair cells.

Protein Attributes:

Sequence length:

3511

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LTLPPSEITL | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q9QZZ4

Pfam:

PF00612

STRING:

10090.ENSMUSP00000071777

String:

Q9QZZ4

UniGene:

Mm.89960

KEGG:

mmu:17910

Uniprot:

Q9QZZ4

FOR

ELISA Kit for Mouse Myosin-XV

CLIA Kit for Mouse Myosin-XV

Polyclonal Antibody for Mouse Myosin-XV

Monoclonal Antibody for Mouse Myosin-XV

Protein for Mouse Myosin-XV

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2."
Liang Y. , Wang A. , Belyantseva I.A. , Anderson D.W. , Probst F.J. , Barber T.D. , Miller W. , Touchman J.W. , Jin L. , Sullivan S.L. , Sellers J.R. , Camper S.A. , Lloyd R.V. , Kachar B. , Friedman T.B. , Fridell R.A.
Genomics61:243-258(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
2.

"Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle."
Belyantseva I.A. , Boger E.T. , Friedman T.B.
Proc. Natl. Acad. Sci. U.S.A.100:13958-13963(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);FUNCTION;SUBCELLULAR LOCATION
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene."
Probst F.J. , Fridell R.A. , Raphael Y. , Saunders T.L. , Wang A. , Liang Y. , Morell R.J. , Touchman J.W. , Lyons R.H. , Noben-Trauth K. , Friedman T.B. , Camper S.A.
Science280:1444-1447(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1168-2970 (ISOFORM 1);VARIANT SH-2 TYR-1779
tissue: Embryo.
5.

"A novel type of myosin encoded by the mouse deafness gene shaker-2."
Wakabayashi Y. , Takahashi Y. , Kikkawa Y. , Okano H. , Mishima Y. , Ushiki T. , Yonekawa H. , Kominami R.
Biochem. Biophys. Res. Commun.248:655-659(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1237-1823;VARIANT SH-2 TYR-1779
strain: C57BL/6.
6.

"Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia."
Belyantseva I.A. , Boger E.T. , Naz S. , Frolenkov G.I. , Sellers J.R. , Ahmed Z.M. , Griffith A.J. , Friedman T.B.
Nat. Cell Biol.7:148-156(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH WHRN
7.

"Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8."
Manor U. , Disanza A. , Grati M. , Andrade L. , Lin H. , Di Fiore P.P. , Scita G. , Kachar B.
Curr. Biol.21:167-172(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EPS8

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