Gene name:
NAMPT (PBEF;PBEF1) ;
Protein name:
Nicotinamide phosphoribosyltransferase (NAmPRTase;Nampt) ;
Alternative:
Visfatin ;Pre-B-cell colony-enhancing factor 1 (Pre-B cell-enhancing factor) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MNPAAEAEFN | ILLATDSYKV | THYKQYPPNT | SKVYSYFECR | EKKTENSKLR |
100:
KVKYEETVFY | GLQYILNKYL | KGKVVTKEKI | QEAKDVYKEH | FQDDVFNEKG |
150:
WNYILEKYDG | HLPIEIKAVP | EGFVIPRGNV | LFTVENTDPE | CYWLTNWIET |
200:
ILVQSWYPIT | VATNSREQKK | ILAKYLLETS | GNLDGLEYKL | HDFGYRGVSS |
250:
QETAGIGASA | HLVNFKGTDT | VAGLALIKKY | YGTKDPVPGY | SVPAAEHSTI |
300:
TAWGKDHEKD | AFEHIVTQFS | SVPVSVVSDS | YDIYNACEKI | WGEDLRHLIV |
350:
SRSTQAPLII | RPDSGNPLDT | VLKVLEILGK | KFPVTENSKG | YKLLPPYLRV |
400:
IQGDGVDINT | LQEIVEGMKQ | KMWSIENIAF | GSGGGLLQKL | TRDLLNCSFK |
450:
CSYVVTNGLG | INVFKDPVAD | PNKRSKKGRL | SLHRTPAGNF | VTLEEGKGDL |
491:
EEYGQDLLHT | VFKNGKVTKS | YSFDEIRKNA | QLNIELEAAH | H
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Rat
Mouse
Human
ELISA Kit for Human NAmPRTase
ELISA Kit for Human NAmPRTase
ELISA Kit for Human NAmPRTase
ELISA Kit for Human NAmPRTase
CLIA Kit for Human NAmPRTase
CLIA Kit for Human NAmPRTase
CLIA Kit for Human NAmPRTase
CLIA Kit for Human NAmPRTase
Polyclonal Antibody for Human NAmPRTase
Polyclonal Antibody for Human NAmPRTase
Polyclonal Antibody for Human NAmPRTase
Polyclonal Antibody for Human NAmPRTase
Monoclonal Antibody for Human NAmPRTase
Monoclonal Antibody for Human NAmPRTase
Monoclonal Antibody for Human NAmPRTase
Monoclonal Antibody for Human NAmPRTase
Protein for Human NAmPRTase
Protein for Human NAmPRTase
Protein for Human NAmPRTase
Protein for Human NAmPRTase
R&D Technical Data
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12% SDS-PAGE analysis
Western blot - Anti-NAMPT antibody
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Precision
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Recovery
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Linearity
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Citations
[1].
Kazem Y M I, El Shebini S M, Moaty M I A, et al
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Trachea .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
tissue :
Skin .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) IN COMPLEXES WITH SUBSTRATE; PRODUCT AND INHIBITOR FK866;ENZYME REGULATION;MUTAGENESIS OF ASP-219; HIS-247 AND ARG-311;SUBUNIT
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Silliman N.
,
Szabo S.
,
Buckhaults P.
,
Farrell C.
,
Meeh P.
,
Markowitz S.D.
,
Willis J.
,
Dawson D.
,
Willson J.K.V.
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Gazdar A.F.
,
Hartigan J.
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Wu L.
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Liu C.
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Parmigiani G.
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Park B.H.
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Bachman K.E.
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Papadopoulos N.
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Vogelstein B.
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Kinzler K.W.
,
Velculescu V.E.
more...
Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : VARIANT [LARGE SCALE ANALYSIS] SER-176