Protein name:
Transcriptional repressor NF-X1 (m-Nfx.1) ;
Alternative:
Nuclear transcription factor, X box-binding protein 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with PABPC1 and PABPC4.
Function:
Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Together with PABPC1 or PABPC4, acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MAEAPPVSGT | FKFNTDAAEF | IPQERKTSGL | NCGTQRRLDS | SRIGRRNYSS |
100:
SPPCHLPRHI | PYEDISAVHQ | HSYASGSKPK | SPQGFFQSSN | KSLKNHGLQN |
150:
QPWQKARNEK | HQNRNKKAQG | LSEQTSDTSS | LESVARSESG | TNPREHSPSE |
200:
SEKEVVIADP | RGAKPKKAAQ | LTYNYGRGPK | AKGRLRSEWG | NRMSPKSEDE |
250:
NTRPVAISHT | DSSDASCRKP | VVDPCVCRRN | EQRRYPQKRP | PWEVEGARPR |
300:
PGRNPPKQES | QRHINAGPKT | NMSPIPKDNL | RERPTKSACD | TGNLAVVSKS |
350:
SRRVNQEKTA | VRRQDPQVLS | PFPRGKQNHM | LKNVETHTGS | LIEQLTTEKY |
400:
ECMVCCELVQ | VTAPVWSCQS | CFHVFHLNCI | KKWARSPASH | ADGQSGWRCP |
450:
ACQNVSAHVP | NTYTCFCGKV | KNPEWSRNEI | PHSCGEVCRK | KQPGQDCPHS |
500:
CNLLCHPGPC | PPCPAFTTKT | CECGRTRHTV | RCGQPVSVHC | SNACENILNC |
550:
GQHHCAELCH | GGQCQPCRII | LNQVCYCGST | SRDVLCGTDV | GKSDGFGDFS |
600:
CLKICGKDLK | CGSHTCSQVC | HPQPCQPCPR | LPHLVRYCPC | GQTPLSQLLE |
650:
HGSNARKTCM | DPVPSCGKVC | GKPLACGSSD | FIHTCEKLCH | EGDCGPCSRT |
700:
SVISCRCSFR | TKELPCTSLK | SEDATFMCDK | RCNKKRLCGR | HKCNEICCVD |
750:
KEHKCPLICG | RKLRCGLHRC | EEPCHRGNCQ | TCWQASFDEL | TCHCGASVIY |
800:
PPVPCGTRPP | ECTQTCARIH | ECDHPVYHSC | HSEEKCPPCT | FLTQKWCMGK |
850:
HELRSNIPCH | LVDISCGLPC | SAMLPCGMHK | CQRLCHKGEC | LVDEACKQPC |
900:
TTPRGDCGHP | CMAPCHPSLP | CPVTACKAKV | ELQCECGRRK | EMVICSEASG |
950:
TYQRIVAISM | ASKITDMQLG | DSVEISKLIT | KKEVQQARLQ | CDEECAALER |
1000:
RKRLAEAFDI | TDDSDPFNVR | SSASKFSDSL | KDDARKDLKF | VSDVEKEMET |
1050:
LVEAVNKGKN | NKKSHCFPPM | NRDHRRIIHD | LAQVYGLESI | SYDSEPKRNV |
1100:
VVTAVRGKSV | CPPTTLTSVI | ERETQTRPPP | PIPHHRHQAD | KAPGSSTLQK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
ELISA Kit for Mouse m-Nfx.1
ELISA Kit for Mouse m-Nfx.1
ELISA Kit for Mouse m-Nfx.1
CLIA Kit for Mouse m-Nfx.1
CLIA Kit for Mouse m-Nfx.1
CLIA Kit for Mouse m-Nfx.1
Polyclonal Antibody for Mouse m-Nfx.1
Polyclonal Antibody for Mouse m-Nfx.1
Polyclonal Antibody for Mouse m-Nfx.1
Monoclonal Antibody for Mouse m-Nfx.1
Monoclonal Antibody for Mouse m-Nfx.1
Monoclonal Antibody for Mouse m-Nfx.1
Protein for Mouse m-Nfx.1
Protein for Mouse m-Nfx.1
Protein for Mouse m-Nfx.1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3)
strain :
C57BL/6J .
strain :
NOD .
tissue :
Diencephalon .
tissue :
Liver .
tissue :
Lung .
tissue :
Placenta .
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PLoS Biol.7:E1000112-E1000112(2009)
[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
C57BL/6J .
tissue :
Egg .