Protein name:
Non-homologous end-joining factor 1 ;
Alternative:
XRCC4-like factor ;Protein cernunnos ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with XRCC4 and the XRCC4-LIG4 complex. Binds DNA in a length-dependent manner.
Function:
DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MEELEQDLLL | QPWAWLQLAE | NSLLAKVSIT | KHGYALLISD | LQQVWHEQVD |
100:
TSVVSQRAKE | LNKRLTAPPA | ALLCHLDEAL | RPLFKDSAHP | SKATFSCDRG |
150:
EEGLILRVQS | ELSGLPFSWH | FHCIPASSSL | VSQHLIHPLM | GVSLALQSHV |
200:
RELAALLRMK | DLEIQAYQES | GAVLSRSRLK | TEPFEENSFL | EQFMAEKLPE |
250:
ACAVGDGKPF | AMSLQSLYVA | VTKQQIQARQ | AHKDSGETQA | SSSTSPRGTD |
295:
NQPEEPVSLS | STLSEPEYEP | VAASGPMHRA | RLVKSKRKKP | RGLFS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse Non-homologous end-joining factor 1
ELISA Kit for Mouse Non-homologous end-joining factor 1
ELISA Kit for Mouse Non-homologous end-joining factor 1
CLIA Kit for Mouse Non-homologous end-joining factor 1
CLIA Kit for Mouse Non-homologous end-joining factor 1
CLIA Kit for Mouse Non-homologous end-joining factor 1
Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
Polyclonal Antibody for Mouse Non-homologous end-joining factor 1
Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
Monoclonal Antibody for Mouse Non-homologous end-joining factor 1
Protein for Mouse Non-homologous end-joining factor 1
Protein for Mouse Non-homologous end-joining factor 1
Protein for Mouse Non-homologous end-joining factor 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain :
C57BL/6J .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
Czech II .
tissue :
Brain .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;DISRUPTION PHENOTYPE