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Index > Protein center > PSMG2(Gene name) > Human
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  • PSMG2 (Gene name),
  • Proteasome assembly chaperone 2 (Protein name ),  PSMG2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PSMG2(HCCA3;PAC2;TNFSF5IP1);
    Protein name:
    Proteasome assembly chaperone 2(PAC-2);
    Alternative:
    Tumor necrosis factor superfamily member 5-induced protein 1;Hepatocellular carcinoma-susceptibility protein 3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer interacts directly with the PSMA5 and PSMA7 proteasome alpha subunits.
    Function:
    Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    264
    Sequence:
    50:
    MFVPCGESAP | DLAGFTLLMP | AVSVGNVGQL | AMDLIISTLN | MSKIGYFYTD | 
    100:
    CLVPMVGNNP | YATTEGNSTE | LSINAEVYSL | PSRKLVALQL | RSIFIKYKSK | 
    150:
    PFCEKLLSWV | KSSGCARVIV | LSSSHSYQRN | DLQLRSTPFR | YLLTPSMQKS | 
    200:
    VQNKIKSLNW | EEMEKSRCIP | EIDDSEFCIR | IPGGGITKTL | YDESCSKEIQ | 
    250:
    MAVLLKFVSE | GDNIPDALGL | VEYLNEWLQI | LKPLSDDPTV | SASRWKIPSS | 
    264:
    WRLLFGSGLP | PALF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human PAC-2
    ELISA Kit for Human PAC-2
    ELISA Kit for Human PAC-2
    CLIA Kit for Human PAC-2
    CLIA Kit for Human PAC-2
    CLIA Kit for Human PAC-2
    Polyclonal Antibody for Human PAC-2
    Polyclonal Antibody for Human PAC-2
    Polyclonal Antibody for Human PAC-2
    Monoclonal Antibody for Human PAC-2
    Monoclonal Antibody for Human PAC-2
    Monoclonal Antibody for Human PAC-2
    Protein for Human PAC-2
    Protein for Human PAC-2
    Protein for Human PAC-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Gene expression in CD34(+) cells from normal bone marrow and leukemic origins."
      Gu J. , Zhang Q.H. , Huang Q.H. , Ren S.X. , Wu X.Y. , Ye M. , Huang C.H. , Fu G. , Zhou J. , Niu C. , Han Z.G. , Chen S.J. , Chen Z.
      Hematol. J.1:206-217(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Hematopoietic stem cell.
    2. 2.
      "Expression of liver cancer associated gene HCCA3."
      Wang Z.-X. , Hu G.-F. , Wang H.-Y. , Wu M.-C.
      World J. Gastroenterol.7:821-825(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Placenta.
    3. 3.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skeletal muscle.
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Pancreas.
    7. 8.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 41-264 (ISOFORM 1)
    8. 9.
      "A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes."
      Hirano Y. , Hendil K.B. , Yashiroda H. , Iemura S. , Nagane R. , Hioki Y. , Natsume T. , Tanaka K. , Murata S.
      Nature437:1381-1385(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION;FUNCTION;INTERACTION WITH PSMA5; PSMA7 AND PSMG1;DEGRADATION BY THE PROTEASOME
    9. 10.
      "20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals."
      Le Tallec B. , Barrault M.-B. , Courbeyrette R. , Guerois R. , Marsolier-Kergoat M.-C. , Peyroche A.
      Mol. Cell27:660-674(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    10. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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