FTH1 Protein for Human(Homo sapiens) | EIAab.comFTH1 Protein for Human(Homo sapiens)

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FTH1 (Gene name),

Ferritin heavy chain (Protein name ), FRIH_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

FTH1(OK/SW-cl.84;PIG15;FTH;FTHL6);

Protein name:

Ferritin heavy chain(Ferritin H subunit);

Alternative:

Cell proliferation-inducing gene 15 protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.

Function:

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

183

Sequence:

50:

100:

150:

183:

DHVTNLRKMG | APESGLAEYL | FDKHTLGDSD | NES

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

134770

STRING:

9606.ENSP00000273550

UniGene:

Hs.524910

Pfam:

PF00210

KEGG:

hsa:2495

SMR:

P02794

String:

P02794

Uniprot:

P02794

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ELISA Kit for Human Ferritin H subunit

Cat.:

E0518r

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96T

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ELISA Kit for Human Ferritin H subunit

Cat.:

E0518h

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96T

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ELISA Kit for Human Ferritin H subunit

MSDS:

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ELISA Kit for Human Ferritin H subunit

Cat.:

E0518m

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96T

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ELISA Kit for Human Ferritin H subunit

Cat.:

E0518p

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Packing:

96T

ELISA Kit for Human Ferritin H subunit

Cat.:

E0518b

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96T

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ELISA Kit for Human Ferritin H subunit

Cat.:

E0518d

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96T

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CLIA Kit for Human Ferritin H subunit

Cat.:

U0518d

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96T

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CLIA Kit for Human Ferritin H subunit

MSDS:

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CLIA Kit for Human Ferritin H subunit

Cat.:

U0518h

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Looking for manual.

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96T

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CLIA Kit for Human Ferritin H subunit

Cat.:

U0518r

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Looking for manual.

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Packing:

96T

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CLIA Kit for Human Ferritin H subunit

Cat.:

U0518b

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MSDS:

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Packing:

96T

CLIA Kit for Human Ferritin H subunit

Cat.:

U0518m

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Packing:

96T

CLIA Kit for Human Ferritin H subunit

Cat.:

U0518p

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96T

Polyclonal Antibody for Human Ferritin H subunit

Cat.:

P0518Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Ferritin H subunit

Cat.:

P0518Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Ferritin H subunit

Cat.:

P0518Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Ferritin H subunit

Monoclonal Antibody for Human Ferritin H subunit

Cat.:

M0518h

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Packing:

40ug

Monoclonal Antibody for Human Ferritin H subunit

Protein for Human Ferritin H subunit

Cat.:

R0518h

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Packing:

1mg

Purity:

>90%

Protein for Human Ferritin H subunit

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family."
Costanzo F. , Santoro C. , Colantuoni V. , Bensi G. , Raugei G. , Romano V. , Cortese R.
EMBO J.3:23-27(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Hepatocyte.
2.

"Structural and functional relationships of human ferritin H and L chains deduced from cDNA clones."
Boyd D. , Vecoli C. , Belcher D.M. , Jain S.K. , Drysdale J.W.
J. Biol. Chem.260:11755-11761(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro."
Chou C.-C. , Gatti R.A. , Fuller M.L. , Concannon P. , Wong A. , Chada S. , Davis R.C. , Salser W.A.
Mol. Cell. Biol.6:566-573(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Structure of gene and pseudogenes of human apoferritin H."
Costanzo F. , Colombo M. , Staempfli S. , Santoro C. , Marone M. , Frank R. , Delius H. , Cortese R.
Nucleic Acids Res.14:721-736(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene."
Hentze M.W. , Keim S. , Papadopoulos P. , O'Brien S. , Modi W. , Drysdale J.W. , Leonard W.J. , Harford J.B. , Klausner R.D.
Proc. Natl. Acad. Sci. U.S.A.83:7226-7230(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Sequence of a cDNA encoding the ferritin H-chain from an 11-week-old human fetal brain."
Dhar M. , Chauthaiwale V.M. , Joshi J.G.
Gene126:275-278(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
7.

"Cloning of a novel full length cDNA for ferritin heavy chain from normal adult human and Alzheimer's brain."
Chauthaiwale V.M. , Dhar M. , McLachlan D.R. , Joshi J.G.
Submitted (1994-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
8.

"Detection of ferritin heavy chain by SEREX: a multifunctional molecule in malignant tumour cells."
Franco A.V. , Gray C.P. , Myers K. , Hersey P.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
9.

"Identification of a human cell proliferation gene 15."
Kim J.W.
Submitted (2003-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
10.

"Identification of immuno-peptidmics that are recognized by tumor-reactive CTL generated from TIL of colon cancer patients."
Shichijo S. , Itoh K.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Colon adenocarcinoma.
11.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cerebellum.
12.

NHLBI resequencing and genotyping service (RS&G)
Submitted (2006-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
13.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
14.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Cervix.
tissue: Colon.
tissue: Lung.
tissue: Ovary.
tissue: Prostate.
tissue: Salivary gland.
15.

"Isolation and characterization of a cDNA clone for human ferritin heavy chain."
Boyd D. , Jain S.K. , Crampton J. , Barrett K.J. , Drysdale J.
Proc. Natl. Acad. Sci. U.S.A.81:4751-4755(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 128-183
16.

"A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload."
Kato J. , Fujikawa K. , Kanda M. , Fukuda N. , Sasaki K. , Takayama T. , Kobune M. , Takada K. , Takimoto R. , Hamada H. , Ikeda T. , Niitsu Y.
Am. J. Hum. Genet.69:191-197(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN HFE5;TISSUE SPECIFICITY
17.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
18.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
19.

"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179 AND SER-183;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
20.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
21.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
22.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-179;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND THR-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
24.

"Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts."
Lawson D.M. , Artymiuk P.J. , Yewdall S.J. , Smith J.M.A. , Livingstone J.C. , Treffry A. , Luzzago A. , Levi S. , Arosio P. , Cesarini G. , Thomas C.D. , Shaw W.V. , Harrison P.M.
Nature349:541-544(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS)
25.

"Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution."
Hempstead P.D. , Yewdall S.J. , Fernie A.R. , Lawson D.M. , Artymiuk P.J. , Rice D.W. , Ford G.C. , Harrison P.M.
J. Mol. Biol.268:424-448(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS)

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