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Index > Protein center > Sost(Gene name) > Rat
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  • Sost (Gene name),
  • Sclerostin (Protein name ),  SOST_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Sost;
    Protein name:
    Sclerostin;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling.
    Function:
    Negative regulator of bone growth.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    213
    Sequence:
    50:
    MQLSLAPCLA | CLLVHAAFVA | VESQGWQAFK | NDATEIIPGL | REYPEPPQEL | 
    100:
    ENNQTMNRAE | NGGRPPHHPY | DTKDVSEYSC | RELHYTRFVT | DGPCRSAKPV | 
    150:
    TELVCSGQCG | PARLLPNAIG | RVKWWRPNGP | DFRCIPDRYR | AQRVQLLCPG | 
    200:
    GAAPRSRKVR | LVASCKCKRL | TRFHNQSELK | DFGPETARPQ | KGRKPRPRAR | 
    213:
    GAKANQAELE | NAY
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Sclerostin
    Cat.:
    E1713r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Sclerostin
    Cat.:
    E1713m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Sclerostin
    Cat.:
    E1713h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Sclerostin
    Cat.:
    E1713b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Sclerostin
    Cat.:
    U1713h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Sclerostin
    Cat.:
    U1713r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Sclerostin
    Cat.:
    U1713m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Sclerostin
    Cat.:
    U1713b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Sclerostin
    Cat.:
    P1713Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Sclerostin
    Polyclonal Antibody for Rat Sclerostin
    Cat.:
    P1713Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Sclerostin
    Cat.:
    P1713Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Sclerostin
    Monoclonal Antibody for Rat Sclerostin
    Monoclonal Antibody for Rat Sclerostin
    Monoclonal Antibody for Rat Sclerostin
    Protein for Rat Sclerostin
    Protein for Rat Sclerostin
    Protein for Rat Sclerostin
    Protein for Rat Sclerostin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    Citations
    References
    1. 1.
      "Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein."
      Brunkow M.E. , Gardner J.C. , Van Ness J. , Paeper B.W. , Kovacevich B.R. , Proll S. , Skonier J.E. , Zhao L. , Sabo P.J. , Fu Y.H. , Alisch R.S. , Gillett L. , Colbert T. , Tacconi P. , Galas D. , Hamersma H. , Beighton P. , Mulligan J.T.
      Am. J. Hum. Genet.68:577-589(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
    2. 2.
      "SOST is a target gene for PTH in bone."
      Keller H. , Kneissel M.
      Bone37:148-158(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOWN-REGULATION BY PTH
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