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Index > Protein center > TIE1(Gene name) > Human
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  • TIE1 (Gene name),
  • Tyrosine-protein kinase receptor Tie-1 (Protein name ),  TIE1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TIE1(TIE);
    Protein name:
    Tyrosine-protein kinase receptor Tie-1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probable protein tyrosine-kinase transmembrane receptor.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1138
    Sequence:
    50:
    MVWRVPPFLL | PILFLASHVG | AAVDLTLLAN | LRLTDPQRFF | LTCVSGEAGA | 
    100:
    GRGSDAWGPP | LLLEKDDRIV | RTPPGPPLRL | ARNGSHQVTL | RGFSKPSDLV | 
    150:
    GVFSCVGGAG | ARRTRVIYVH | NSPGAHLLPD | KVTHTVNKGD | TAVLSARVHK | 
    200:
    EKQTDVIWKS | NGSYFYTLDW | HEAQDGRFLL | QLPNVQPPSS | GIYSATYLEA | 
    250:
    SPLGSAFFRL | IVRGCGAGRW | GPGCTKECPG | CLHGGVCHDH | DGECVCPPGF | 
    300:
    TGTRCEQACR | EGRFGQSCQE | QCPGISGCRG | LTFCLPDPYG | CSCGSGWRGS | 
    350:
    QCQEACAPGH | FGADCRLQCQ | CQNGGTCDRF | SGCVCPSGWH | GVHCEKSDRI | 
    400:
    PQILNMASEL | EFNLETMPRI | NCAAAGNPFP | VRGSIELRKP | DGTVLLSTKA | 
    450:
    IVEPEKTTAE | FEVPRLVLAD | SGFWECRVST | SGGQDSRRFK | VNVKVPPVPL | 
    500:
    AAPRLLTKQS | RQLVVSPLVS | FSGDGPISTV | RLHYRPQDST | MDWSTIVVDP | 
    550:
    SENVTLMNLR | PKTGYSVRVQ | LSRPGEGGEG | AWGPPTLMTT | DCPEPLLQPW | 
    600:
    LEGWHVEGTD | RLRVSWSLPL | VPGPLVGDGF | LLRLWDGTRG | QERRENVSSP | 
    650:
    QARTALLTGL | TPGTHYQLDV | QLYHCTLLGP | ASPPAHVLLP | PSGPPAPRHL | 
    700:
    HAQALSDSEI | QLTWKHPEAL | PGPISKYVVE | VQVAGGAGDP | LWIDVDRPEE | 
    750:
    TSTIIRGLNA | STRYLFRMRA | SIQGLGDWSN | TVEESTLGNG | LQAEGPVQES | 
    800:
    RAAEEGLDQQ | LILAVVGSVS | ATCLTILAAL | LTLVCIRRSC | LHRRRTFTYQ | 
    850:
    SGSGEETILQ | FSSGTLTLTR | RPKLQPEPLS | YPVLEWEDIT | FEDLIGEGNF | 
    900:
    GQVIRAMIKK | DGLKMNAAIK | MLKEYASEND | HRDFAGELEV | LCKLGHHPNI | 
    950:
    INLLGACKNR | GYLYIAIEYA | PYGNLLDFLR | KSRVLETDPA | FAREHGTAST | 
    1000:
    LSSRQLLRFA | SDAANGMQYL | SEKQFIHRDL | AARNVLVGEN | LASKIADFGL | 
    1050:
    SRGEEVYVKK | TMGRLPVRWM | AIESLNYSVY | TTKSDVWSFG | VLLWEIVSLG | 
    1100:
    GTPYCGMTCA | ELYEKLPQGY | RMEQPRNCDD | EVYELMRQCW | RDRPYERPPF | 
    1138:
    AQIALQLGRM | LEARKAYVNM | SLFENFTYAG | IDATAEEA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    UniGene:
    Pfam:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    E0125h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    E0125m
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    E0125b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    U0125b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    U0125m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    U0125h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    P0125Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Cat.:
    P0125Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Monoclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Monoclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Monoclonal Antibody for Human Tyrosine-protein kinase receptor Tie-1
    Protein for Human Tyrosine-protein kinase receptor Tie-1
    Protein for Human Tyrosine-protein kinase receptor Tie-1
    Protein for Human Tyrosine-protein kinase receptor Tie-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains."
      Partanen J. , Armstrong E. , Maekelae T.P. , Korhonen J. , Sandberg M. , Renkonen R. , Knuutila S. , Huebner K. , Alitalo K.
      Mol. Cell. Biol.12:1698-1707(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      Partanen J.M.
      Submitted (1993-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    3. 3.
      "Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis."
      Jin P. , Zhang J. , Sumariwalla P.F. , Ni I. , Jorgensen B. , Crawford D. , Phillips S. , Feldmann M. , Shepard H.M. , Paleolog E.M.
      Arthritis Res. Ther.10:R73-R73(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);ALTERNATIVE SPLICING
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
    6. 6.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-36
    7. 7.
      "Multiple angiopoietin recombinant proteins activate the Tie1 receptor tyrosine kinase and promote its interaction with Tie2."
      Saharinen P. , Kerkela K. , Ekman N. , Marron M. , Brindle N. , Lee G.M. , Augustin H. , Koh G.Y. , Alitalo K.
      J. Cell Biol.169:239-243(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TEK/TIE2;SUBCELLULAR LOCATION;PHOSPHORYLATION
    8. 8.
      "Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands."
      Seegar T.C. , Eller B. , Tzvetkova-Robev D. , Kolev M.V. , Henderson S.C. , Nikolov D.B. , Barton W.A.
      Mol. Cell37:643-655(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TEK/TIE2;SUBCELLULAR LOCATION;FUNCTION
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