Protein name:
Tumor necrosis factor ligand superfamily member 12 ;
Alternative:
TNF-related weak inducer of apoptosis (TWEAK) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q.
Function:
Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
Subcellular Location:
Tumor necrosis factor ligand superfamily member 12, secreted form
Secreted
Protein Attributes:
50:
MAARRSQRRR | GRRGEPGTAL | LAPLVLSLGL | ALACLGLLLV | VVSLGSWATL |
100:
SAQEPSQEEL | TAEDRREPPE | LNPQTEESQD | VVPFLEQLVR | PRRSAPKGRK |
150:
ARPRRAIAAH | YEVHPRPGQD | GAQAGVDGTV | SGWEETKINS | SSPLRYDRQI |
200:
GEFTVIRAGL | YYLYCQVHFD | EGKAVYLKLD | LLVNGVLALR | CLEEFSATAA |
249:
SSPGPQLRLC | QVSGLLPLRP | GSSLRIRTLP | WAHLKAAPFL | TYFGLFQVH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
Protein for Mouse Tumor necrosis factor ligand superfamily member 12
Protein for Mouse Tumor necrosis factor ligand superfamily member 12
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 25-249
tissue :
Peritoneal macrophage .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 107-249
strain :
C57BL/6J .
tissue :
Retina .