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Index > Protein center > Tnfsf12(Gene name) > Mouse
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  • Tnfsf12 (Gene name),
  • Tumor necrosis factor ligand superfamily member 12 (Protein name ),  TNF12_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tnfsf12;
    Protein name:
    Tumor necrosis factor ligand superfamily member 12;
    Alternative:
    TNF-related weak inducer of apoptosis(TWEAK);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotrimer (Potential). Interacts with the angiogenic factor AGGF1/VG5Q.
    Function:
    Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.
    Subcellular Location:
    Tumor necrosis factor ligand superfamily member 12, secreted form Secreted
    Protein Attributes:
    Sequence length:
    249
    Sequence:
    50:
    MAARRSQRRR | GRRGEPGTAL | LAPLVLSLGL | ALACLGLLLV | VVSLGSWATL | 
    100:
    SAQEPSQEEL | TAEDRREPPE | LNPQTEESQD | VVPFLEQLVR | PRRSAPKGRK | 
    150:
    ARPRRAIAAH | YEVHPRPGQD | GAQAGVDGTV | SGWEETKINS | SSPLRYDRQI | 
    200:
    GEFTVIRAGL | YYLYCQVHFD | EGKAVYLKLD | LLVNGVLALR | CLEEFSATAA | 
    249:
    SSPGPQLRLC | QVSGLLPLRP | GSSLRIRTLP | WAHLKAAPFL | TYFGLFQVH
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    KEGG:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    E1883h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    E1883m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    U1883m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    U1883h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    P1883Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
    Cat.:
    P1883Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
    Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 12
    Protein for Mouse Tumor necrosis factor ligand superfamily member 12
    Protein for Mouse Tumor necrosis factor ligand superfamily member 12

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      Chicheportiche Y. , Bixler S. , Tizard R. , Browning J.L.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis."
      Chicheportiche Y. , Bourdon P.R. , Xu H. , Hsu Y.-M. , Scott H. , Hession C. , Garcia I. , Browning J.L.
      J. Biol. Chem.272:32401-32410(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-249
      tissue: Peritoneal macrophage.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 107-249
      strain: C57BL/6J.
      tissue: Retina.
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