Gene name:
Tnfsf13 (April) ;
Protein name:
Tumor necrosis factor ligand superfamily member 13 ;
Alternative:
A proliferation-inducing ligand (APRIL) ;
CD:
CD256 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subcellular Location:
Secreted
Protein Attributes:
50:
MPASSPGHMG | GSVREPALSV | ALWLSWGAVL | GAVTCAVALL | IQQTELQSLR |
100:
REVSRLQRSG | GPSQKQGERP | WQSLWEQSPD | VLEAWKDGAK | SRRRRAVLTQ |
150:
KHKKKHSVLH | LVPVNITSKA | DSDVTEVMWQ | PVLRRGRGLE | AQGDIVRVWD |
200:
TGIYLLYSQV | LFHDVTFTMG | QVVSREGQGR | RETLFRCIRS | MPSDPDRAYN |
241:
SCYSAGVFHL | HQGDIITVKI | PRANAKLSLS | PHGTFLGFVK | L
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 13
ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 13
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 13
CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 13
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 13
Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 13
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 13
Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 13
Protein for Mouse Tumor necrosis factor ligand superfamily member 13
Protein for Mouse Tumor necrosis factor ligand superfamily member 13
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity."
Yu G.
,
Boone T.
,
Delaney J.
,
Hawkins N.
,
Kelley M.J.
,
Ramakrishnan M.
,
McCabe S.
,
Qiu W.R.
,
Kornuc M.
,
Xia X.-Z.
,
Guo J.
,
Stolina M.
,
Boyle W.J.
,
Sarosi I.
,
Hsu H.
,
Senaldi G.
,
Theill L.E.
Nat. Immunol.1:252-256(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
2.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Tongue .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
129 .
tissue :
Mammary gland .
4.
"APRIL promotes B-1 cell-associated neoplasm."
Planelles L.
,
Carvalho-Pinto C.E.
,
Hardenberg G.
,
Smaniotto S.
,
Savino W.
,
Gomez-Caro R.
,
Alvarez-Mon M.
,
de Jong J.
,
Eldering E.
,
Martinez-A C.
,
Medema J.P.
,
Hahne M.
Cancer Cell6:399-408(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TRANSGENIC MICE
5.
"Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding."
Hymowitz S.G.
,
Patel D.R.
,
Wallweber H.J.
,
Runyon S.
,
Yan M.
,
Yin J.
,
Shriver S.K.
,
Gordon N.C.
,
Pan B.
,
Skelton N.J.
,
Kelley R.F.
,
Starovasnik M.A.
J. Biol. Chem.280:7218-7227(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 104-241 IN COMPLEX WITH HUMAN TNFRSF17;DISULFIDE BONDS