Tnfsf18 ELISA Kit for Mouse(Mus musculus) | EIAab.comTnfsf18 ELISA Kit for Mouse(Mus musculus)

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Tnfsf18 (Gene name),

Tumor necrosis factor ligand superfamily member 18 (Protein name ), TNF18_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tnfsf18(Gitrl);

Protein name:

Tumor necrosis factor ligand superfamily member 18;

Alternative:

Glucocorticoid-induced TNF-related ligand;GITR ligand(GITRL);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotrimer. Homodimer.

Function:

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

Subcellular Location:

Cell membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

173

Sequence:

50:

100:

150:

173:

KDHIQKTNTY | WGIILMPDLP | FIS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00229

UniGene:

Mm.276823

SMR:

Q7TS55

KEGG:

mmu:240873

Uniprot:

Q7TS55

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ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

E8960h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

E8960m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

U8960h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

U8960m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

P8960Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 18

Cat.:

P8960Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Tumor necrosis factor ligand superfamily member 18

Protein for Mouse Tumor necrosis factor ligand superfamily member 18

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells."
Yu K.Y. , Kim H.S. , Song S.Y. , Min S.S. , Jeong J.J. , Youn B.S.
Biochem. Biophys. Res. Commun.310:433-438(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: 129/J.
2.

"Cloning and characterization of GITR ligand."
Kim J.D. , Choi B.K. , Bae J.S. , Lee U.H. , Han I.S. , Lee H.W. , Youn B.S. , Vinay D.S. , Kwon B.S.
Genes Immun.4:564-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY
strain: BALB/c.
3.

"Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells."
Tone M. , Tone Y. , Adams E. , Yates S.F. , Frewin M.R. , Cobbold S.P. , Waldmann H.
Proc. Natl. Acad. Sci. U.S.A.100:15059-15064(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;INDUCTION;TISSUE SPECIFICITY
strain: CBA/Ca.
4.

"The natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression."
Ji H.B. , Liao G. , Faubion W.A. , Abadia-Molina A.C. , Cozzo C. , Laroux F.S. , Caton A. , Terhorst C.
J. Immunol.172:5823-5827(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBUNIT
strain: C57BL/6.
tissue: Spleen.
5.

"Cloning and characterization of the mouse ortholog of human GITR ligand (TNFSF18)."
Bianchini R. , Nocentini G. , Ronchetti S. , Ayroldi E. , Riccardi C.
Submitted (2003-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: DBA/2J.
6.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
8.

"Glucocorticoid-induced tumor necrosis factor receptor family-related ligand triggering upregulates vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 and promotes leukocyte adhesion."
Lacal P.M. , Petrillo M.G. , Ruffini F. , Muzi A. , Bianchini R. , Ronchetti S. , Migliorati G. , Riccardi C. , Graziani G. , Nocentini G.
J. Pharmacol. Exp. Ther.347:164-172(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Glucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestine."
Liao G. , van Driel B. , Magelky E. , O'Keeffe M.S. , de Waal Malefyt R. , Engel P. , Herzog R.W. , Mizoguchi E. , Bhan A.K. , Terhorst C.
FASEB J.28:474-484(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
10.

"Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily."
Chattopadhyay K. , Ramagopal U.A. , Brenowitz M. , Nathenson S.G. , Almo S.C.
Proc. Natl. Acad. Sci. U.S.A.105:635-640(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.09 ANGSTROMS) OF 46-173;SUBUNIT;DISULFIDE BOND
11.

"Structural basis for ligand-mediated mouse GITR activation."
Zhou Z. , Tone Y. , Song X. , Furuuchi K. , Lear J.D. , Waldmann H. , Tone M. , Greene M.I. , Murali R.
Proc. Natl. Acad. Sci. U.S.A.105:641-645(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 43-173;FUNCTION;SUBUNIT;DISULFIDE BOND
12.

"1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells."
Chattopadhyay K. , Ramagopal U.A. , Nathenson S.G. , Almo S.C.
Acta Crystallogr. D65:434-439(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.76 ANGSTROMS) OF 46-173;GLYCOSYLATION;SUBUNIT;DISULFIDE BOND

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