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Index > Protein center > LTB(Gene name) > Human
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  • LTB (Gene name),
  • Lymphotoxin-beta (Protein name ),  TNFC_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    LTB(TNFC;TNFSF3);
    Protein name:
    Lymphotoxin-beta(LT-beta);
    Alternative:
    Tumor necrosis factor ligand superfamily member 3;Tumor necrosis factor C(TNF-C);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.
    Function:
    Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    244
    Sequence:
    50:
    MGALGLEGRG | GRLQGRGSLL | LAVAGATSLV | TLLLAVPITV | LAVLALVPQD | 
    100:
    QGGLVTETAD | PGAQAQQGLG | FQKLPEEEPE | TDLSPGLPAA | HLIGAPLKGQ | 
    150:
    GLGWETTKEQ | AFLTSGTQFS | DAEGLALPQD | GLYYLYCLVG | YRGRAPPGGG | 
    200:
    DPQGRSVTLR | SSLYRAGGAY | GPGTPELLLE | GAETVTPVLD | PARRQGYGPL | 
    244:
    WYTSVGFGGL | VQLRRGERVY | VNISHPDMVD | FARGKTFFGA | VMVG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    MIM:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human LT-beta
    Cat.:
    E1560h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human LT-beta
    Cat.:
    E1560m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LT-beta
    Cat.:
    E1560p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LT-beta
    Cat.:
    U1560p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LT-beta
    Cat.:
    U1560m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LT-beta
    Cat.:
    U1560h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human LT-beta
    Cat.:
    P1560Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LT-beta
    Polyclonal Antibody for Human LT-beta
    Cat.:
    P1560Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human LT-beta
    Monoclonal Antibody for Human LT-beta
    Monoclonal Antibody for Human LT-beta
    Protein for Human LT-beta
    Protein for Human LT-beta
    Protein for Human LT-beta

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    Precision
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    Linearity
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    References
    1. 1.
      "Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface."
      Browning J.L. , Ngam-Ek A. , Lawton P. , Demarinis J. , Tizard R. , Chow E.P. , Hession C. , O'Brine-Greco B. , Foley S.F. , Ware C.F.
      Cell72:847-856(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
      tissue: T-cell.
    2. 2.
      "Identification of two lymphotoxin beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas."
      Warzocha K. , Renard N. , Charlot C. , Bienvenu J. , Coiffier B. , Salles G.
      Biochem. Biophys. Res. Commun.238:273-276(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
    3. 3.
      "A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC."
      Neville M.J. , Campbell R.D.
      J. Immunol.162:4745-4754(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM 1)
    4. 4.
      "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."
      Xie T. , Rowen L. , Aguado B. , Ahearn M.E. , Madan A. , Qin S. , Campbell R.D. , Hood L.
      Genome Res.13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
      Shiina S. , Tamiya G. , Oka A. , Inoko H.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2001-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLU-70 AND PRO-111
    7. 7.
      NIEHS SNPs program
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-84 AND PHE-87
    8. 8.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Spleen.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Colon.
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