CD40 ELISA Kit for Human(Homo sapiens) | EIAab.comCD40 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CD40(Gene name) > Human

CD40 (Gene name),

Tumor necrosis factor receptor superfamily member 5 (Protein name ), TNR5_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD40(TNFRSF5);

Protein name:

Tumor necrosis factor receptor superfamily member 5;

Alternative:

Bp50;B-cell surface antigen CD40;CDw40;CD40L receptor;

CD:

CD40;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6.

Function:

Receptor for TNFSF5/CD40LG.

Subcellular Location:

Isoform II Secreted

Protein Attributes:

Sequence length:

277

Sequence:

50:

100:

150:

200:

250:

277:

VQETLHGCQP | VTQEDGKESR | ISVQERQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.472860

KEGG:

hsa:958

STRING:

9606.ENSP00000361359

MIM:

109535

SMR:

P25942

String:

P25942

Pfam:

PF00020

Uniprot:

P25942

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

E9130h

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96T

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

E9130m

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96T

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

E9130p

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 5

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ELISA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

E9130b

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96T

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 5

MSDS:

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CLIA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

U9130p

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

U9130m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

U9130h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

U9130b

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Packing:

96T

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

P9130Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 5

Cat.:

P9130Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Tumor necrosis factor receptor superfamily member 5

Monoclonal Antibody for Human Tumor necrosis factor receptor superfamily member 5

Protein for Human Tumor necrosis factor receptor superfamily member 5

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas."
Stamenkovic I. , Clark E.A. , Seed B.
EMBO J.8:1403-1410(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM I)
2.

"Regulation of CD40 function by its isoforms generated through alternative splicing."
Tone M. , Tone Y. , Fairchild P.J. , Wykes M. , Waldmann H.
Proc. Natl. Acad. Sci. U.S.A.98:1751-1756(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM II)
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM I)
4.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM I)
tissue: Kidney.
5.

NIEHS SNPs program
Submitted (2003-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LEU-124 AND ALA-227
6.

Livingston R.J. , Shaffer T. , McFarland I. , Nguyen C.P. , Stanaway I.B. , Rajkumar N. , Johnson E.J. , da Ponte S.H. , Willa H. , Ahearn M.O. , Bertucci C. , Acklestad J. , Carroll A. , Swanson J. , Gildersleeve H.I. , Nickerson D.A.
Submitted (2006-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM I)
tissue: Ovary.
10.

"Transcripts of CD40 isoform in peripheral mononuclear cells."
He X. , Xu L. , Zeng Y.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-223 (ISOFORM I)
tissue: Leukocyte.
11.

"Biochemical characteristics and partial amino acid sequence of the receptor-like human B cell and carcinoma antigen CDw40."
Braesch-Andersen S. , Paulie S. , Koho H. , Nika H. , Aspenstroem P. , Perlmann P.
J. Immunol.142:562-567(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-50;SUBUNIT;VARIANTS GLN-26; GLY-35 AND THR-39
tissue: Lymphoma.
tissue: Urinary bladder carcinoma.
12.

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Zhang Z. , Henzel W.J.
Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-35
13.

"Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells."
Khandekar S.S. , Silverman C. , Wells-Marani J. , Bacon A.M. , Birrell H. , Brigham-Burke M. , DeMarini D.J. , Jonak Z.L. , Camilleri P. , Fishman-Lobell J.
Protein Expr. Purif.23:301-310(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-30
14.

"A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40."
Sato T. , Irie S. , Reed J.C.
FEBS Lett.358:113-118(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF3
15.

"Involvement of CRAF1, a relative of TRAF, in CD40 signaling."
Cheng G. , Cleary A.M. , Ye Z.S. , Hong D.I. , Lederman S. , Baltimore D.
Science267:1494-1498(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF3
16.

"CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization."
Pullen S.S. , Miller H.G. , Everdeen D.S. , Dang T.T. , Crute J.J. , Kehry M.R.
Biochemistry37:11836-11845(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF1; TRAF2; TRAF3 AND TRAF5
17.

"Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)."
Mizushima S. , Fujita M. , Ishida T. , Azuma S. , Kato K. , Hirai M. , Otsuka M. , Yamamoto T. , Inoue J.
Gene207:135-140(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF5
18.

"Tumor necrosis factor receptor-associated factor 6 (TRAF6) stimulates extracellular signal-regulated kinase (ERK) activity in CD40 signaling along a ras-independent pathway."
Kashiwada M. , Shirakata Y. , Inoue J. , Nakano H. , Okazaki K. , Okumura K. , Yamamoto T. , Nagaoka H. , Takemori T.
J. Exp. Med.187:237-244(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TRAF6
19.

"Construction and analysis of a detailed three-dimensional model of the ligand binding domain of the human B cell receptor CD40."
Bajorath J. , Aruffo A.
Proteins27:59-70(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 24-144
20.

"The role of polar interactions in the molecular recognition of CD40L with its receptor CD40."
Singh J. , Garber E. , van Vlijmen H. , Karpsusas M. , Hsu Y.-M. , Zheng Z. , Naismith J.H. , Thomas D.
Protein Sci.7:1124-1135(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 26-186 IN COMPLEX WITH CD40LG
21.

"Molecular basis for CD40 signaling mediated by TRAF3."
Ni C.Z. , Welsh K. , Leo E. , Chiou C.K. , Wu H. , Reed J.C. , Ely K.R.
Proc. Natl. Acad. Sci. U.S.A.97:10395-10399(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS) OF 247-266 IN COMPLEX WITH TRAF3
22.

"Downstream regulator TANK binds to the CD40 recognition site on TRAF3."
Li C. , Ni C.Z. , Havert M.L. , Cabezas E. , He J. , Kaiser D. , Reed J.C. , Satterthwait A.C. , Cheng G. , Ely K.R.
Structure10:403-411(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 178-195 IN COMPLEX WITH TRAF3
23.

"Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM."
Ferrari S. , Giliani S. , Insalaco A. , Al-Ghonaium A. , Soresina A.R. , Loubser M. , Avanzini M.A. , Marconi M. , Badolato R. , Ugazio A.G. , Levy Y. , Catalan N. , Durandy A. , Tbakhi A. , Notarangelo L.D. , Plebani A.
Proc. Natl. Acad. Sci. U.S.A.98:12614-12619(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIGM3 ARG-83

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