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Index > Protein center > Fas(Gene name) > Rat
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  • Fas (Gene name),
  • Tumor necrosis factor receptor superfamily member 6 (Protein name ),  TNR6_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Fas(Apt1;Tnfrsf6);
    Protein name:
    Tumor necrosis factor receptor superfamily member 6;
    Alternative:
    FASLG receptor;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;
    CD:
    CD95;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Binds DAXX and RIPK1. Interacts with HIPK3. Part of a complex containing HIPK3 and FADD. Interacts with BRE and FEM1B (By similarity). Interacts with FADD.
    Function:
    Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    324
    Sequence:
    50:
    MLWIMAVLPL | VLAGPELNVR | MQGTDSIFEG | LELKRSVRET | DNNCSEGLYQ | 
    100:
    VGPFCCQPCQ | PGERKVKDCT | TSGGAPTCHP | CTEGEEYTDR | KHYSDKCRRC | 
    150:
    AFCDEGHGLE | VETNCTRTQN | TKCRCKENFY | CNASLCDHCY | HCTSCGLEDI | 
    200:
    LEPCTRTSNT | KCKKQSSNYK | LLWLLILPGL | AILFVFIYKR | YRKRQPGDPE | 
    250:
    SGIPSPESVP | MNVSDVNLNK | YIWRTAEKMK | ICDAKKFARQ | HKIPESKIDE | 
    300:
    IEHNSPQDAA | EQKIQLLQCW | YQSHGKTGAC | QALIQGLRKA | NRCDIAEEIQ | 
    324:
    AMVWEDHENS | ISNSRNENEG | QSLE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    E0030h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    E0030m
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    MSDS:
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    96T
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    ELISA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    E0030r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    E0030p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    E0030b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    U0030h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    U0030m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    U0030p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    U0030r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    U0030b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Polyclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Polyclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    P0030Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    P0030Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Cat.:
    P0030Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Monoclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Monoclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Monoclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Monoclonal Antibody for Rat Tumor necrosis factor receptor superfamily member 6
    Protein for Rat Tumor necrosis factor receptor superfamily member 6
    Protein for Rat Tumor necrosis factor receptor superfamily member 6
    Protein for Rat Tumor necrosis factor receptor superfamily member 6
    Protein for Rat Tumor necrosis factor receptor superfamily member 6
    Protein for Rat Tumor necrosis factor receptor superfamily member 6

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    References
    1. 1.
      "A variant mRNA species encoding a truncated form of Fas antigen in the rat liver."
      Kimura K. , Yamamoto M. , Wakatsuki T.
      Biochem. Biophys. Res. Commun.198:666-674(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
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