Vdr ELISA Kit for Rat(Rattus norvegicus) | EIAab.comVdr ELISA Kit for Rat(Rattus norvegicus)

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Vdr (Gene name),

Vitamin D3 receptor (Protein name ), VDR_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Vdr(Nr1i1);

Protein name:

Vitamin D3 receptor(VDR);

Alternative:

Nuclear receptor subfamily 1 group I member 1;1,25-dihydroxyvitamin D3 receptor;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer in the absence of bound vitamin D3. Heterodimer with RXRA after vitamin D3 binding. Interacts with SMAD3. Interacts with MED1, NCOA1, NCOA2, NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts (in a ligand-dependent manner) with BAZ1B/WSTF.

Function:

Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

423

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

423:

SFQPENSMKL | TPLVLEVFGN | EIS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000011601

Pfam:

PF00104

String:

P13053

SMR:

P13053

UniGene:

Rn.10911

KEGG:

rno:24873

Uniprot:

P13053

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ELISA Kit for Rat VDR

Cat.:

E0475r

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96T

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ELISA Kit for Rat VDR

Cat.:

E0475h

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96T

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ELISA Kit for Rat VDR

Cat.:

E0475m

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96T

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ELISA Kit for Rat VDR

Cat.:

E0475b

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96T

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ELISA Kit for Rat VDR

Cat.:

E0475p

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96T

ELISA Kit for Rat VDR

Cat.:

E0475c

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96T

CLIA Kit for Rat VDR

Cat.:

U0475c

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96T

CLIA Kit for Rat VDR

Cat.:

U0475p

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Packing:

96T

CLIA Kit for Rat VDR

Cat.:

U0475h

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96T

CLIA Kit for Rat VDR

Cat.:

U0475b

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96T

CLIA Kit for Rat VDR

Cat.:

U0475r

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96T

CLIA Kit for Rat VDR

Cat.:

U0475m

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96T

Polyclonal Antibody for Rat VDR

Cat.:

P0475Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat VDR

Cat.:

P0475Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat VDR

Cat.:

P0475Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat VDR

Protein for Rat VDR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Structure and regulation of the rat 1,25-dihydroxyvitamin D3 receptor."
Burmester J.K. , Wiese R.J. , Maeda N. , Deluca H.
Proc. Natl. Acad. Sci. U.S.A.85:9499-9502(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.

"Isolation and expression of rat 1,25-dihydroxyvitamin D3 receptor cDNA."
Burmester J.K. , Maeda N. , Deluca H.F.
Proc. Natl. Acad. Sci. U.S.A.85:1005-1009(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 58-423
tissue: Kidney.
3.

"A new family of nuclear receptor coregulators that integrates nuclear receptor signaling through CBP."
Mahajan M.A. , Samuels H.H.
Mol. Cell. Biol.20:5048-5063(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA6
4.

"Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide."
Vanhooke J.L. , Benning M.M. , Bauer C.B. , Pike J.W. , DeLuca H.F.
Biochemistry43:4101-4110(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 116-423 IN COMPLEXES WITH VITAMIN D3 ANALOGS AND MED1
5.

"New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations."
Vanhooke J.L. , Tadi B.P. , Benning M.M. , Plum L.A. , DeLuca H.F.
Arch. Biochem. Biophys.460:161-165(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS) OF 116-423 IN COMPLEXES WITH VITAMIN D3 ANALOGS AND MED1;FUNCTION

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