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Index > Protein center > XIRP1(Gene name) > Human
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  • XIRP1 (Gene name),
  • Xin actin-binding repeat-containing protein 1 (Protein name ),  XIRP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    XIRP1(CMYA1;XIN);
    Protein name:
    Xin actin-binding repeat-containing protein 1;
    Alternative:
    Cardiomyopathy-associated protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CTNNB1 (By similarity). Interacts with F-actin, FLNC and VASP.
    Function:
    Protects actin filaments from depolymerization.
    Subcellular Location:
    Cell junction Colocalizes with actin stress fibers.
    Protein Attributes:
    Sequence length:
    1843
    Sequence:
    50:
    MADTQTQVAP | TPTMRMATAE | DLPLPPPPAL | EDLPLPPPKE | SFSKFHQQRQ | 
    100:
    ASELRRLYRH | IHPELRKNLA | EAVAEDLAEV | LGSEEPTEGD | VQCMRWIFEN | 
    150:
    WRLDAIGEHE | RPAAKEPVLC | GDVQATSRKF | EEGSFANSTD | QEPTRPQPGG | 
    200:
    GDVRAARWLF | ETKPLDELTG | QAKELEATVR | EPAASGDVQG | TRMLFETRPL | 
    250:
    DRLGSRPSLQ | EQSPLELRSE | IQELKGDVKK | TVKLFQTEPL | CAIQDAEGAI | 
    300:
    HEVKAACREE | IQSNAVRSAR | WLFETRPLDA | INQDPSQVRV | IRGISLEEGA | 
    350:
    RPDVSATRWI | FETQPLDAIR | EILVDEKDFQ | PSPDLIPPGP | DVQQQQHLFE | 
    400:
    TRALDTLKGD | EEAGAEAPPK | EEVVPGDVRS | TLWLFETKPL | DAFRDKVQVG | 
    450:
    HLQRVDPQDG | EGHLSSDSSS | ALPFSQSAPQ | RDELKGDVKT | FKNLFETLPL | 
    500:
    DSIGQGEVLA | HGSPSREEGT | DSAGQAQGIG | SPVYAMQDSK | GRLHALTSVS | 
    550:
    REQIVGGDVQ | GYRWMFETQP | LDQLGRSPST | IDVVRGITRQ | EVVAGDVGTA | 
    600:
    RWLFETQPLE | MIHQREQQER | QKEEGKSQGD | PQPEAPPKGD | VQTIRWLFET | 
    650:
    CPMSELAEKQ | GSEVTDPTAK | AEAQSCTWMF | KPQPVDRPVG | SREQHLQVSQ | 
    700:
    VPAGERQTDR | HVFETEPLQA | SGRPCGRRPV | RYCSRVEIPS | GQVSRQKEVF | 
    750:
    QALEAGKKEE | QEPRVIAGSI | PAGSVHKFTW | LFENCPMGSL | AAESIQGGNL | 
    800:
    LEEQPMSPSG | NRMQESQETA | AEGTLRTLHA | TPGILHHGGI | LMEARGPGEL | 
    850:
    CLAKYVLSGT | GQGHPYIRKE | ELVSGELPRI | ICQVLRRPDV | DQQGLLVQED | 
    900:
    PTGQLQLKPL | RLPTPGSSGN | IEDMDPELQQ | LLACGLGTSV | ARTGLVMQET | 
    950:
    EQGLVALTAY | SLQPRLTSKA | SERSSVQLLA | SCIDKGDLSG | LHSLRWEPPA | 
    1000:
    DPSPVPASEG | AQSLHPTESI | IHVPPLDPSM | GMGHLRASGA | TPCPPQAIGK | 
    1050:
    AVPLAGEAAA | PAQLQNTEKQ | EDSHSGQKGM | AVLGKSEGAT | TTPPGPGAPD | 
    1100:
    LLAAMQSLRM | ATAEAQSLHQ | QVLNKHKQGP | TPTATSNPIQ | DGLRKAGATQ | 
    1150:
    SNIRPGGGSD | PRIPAAPRKV | SREEQALPRG | LPGGWVTIQD | GIYTAHPVRT | 
    1200:
    FDPPGGVQLS | QREPQSRHRE | TALSVQAPRP | LQGGPGQSTG | PGREEPGGCT | 
    1250:
    QMAWGPPGKA | MAEVCPGGLQ | AAETTLKTAP | LGRHILASGP | QAAGASPHPH | 
    1300:
    NAFVPPPPTL | PAAVTGPDFP | AGAHRAEDSI | QQASEPLKDP | LLHSHSSPAG | 
    1350:
    QRTPGGSQTK | TPKLDPTMPP | KKKPQLPPKP | AHLTQSHPPQ | RLPKPLPLSP | 
    1400:
    SFSSEVGQRE | HQRGERDTAI | PQPAKVPTTV | DQGHIPLARC | PSGHSQPSLQ | 
    1450:
    HGLSTTAPRP | TKNQATGSNA | QSSEPPKLNA | LNHDPTSPQW | GPGPSGEQPM | 
    1500:
    EGSHQGAPES | PDSLQRNQKE | LQGLLNQVQA | LEKEAASSVD | VQALRRLFEA | 
    1550:
    VPQLGGAAPQ | APAAHQKPEA | SVEQAFGELT | RVSTEVAQLK | EQTLARLLDI | 
    1600:
    EEAVHKALSS | MSSLQPEASA | RGHFQGPPKD | HSAHKISVTV | SSSARPSGSG | 
    1650:
    QEVGGQTAVK | NQAKVECHTE | AQSQVKIRNH | TEARGHTAST | APSTRRQETS | 
    1700:
    REYLCPPRVL | PSSRDSPSSP | TFISIQSATR | KPLETPSFKG | NPDVSVKSTQ | 
    1750:
    LAQDIGQALL | HQKGVQDKTG | KKDITQCSVQ | PEPAPPSASP | LPRGWQKSVL | 
    1800:
    ELQTGPGSSQ | HYGAMRTVTE | QYEEVDQFGN | TVLMSSTTVT | EQAEPPRNPG | 
    1843:
    SHLGLHASPL | LRQFLHSPAG | FSSDLTEAET | VQVSCSYSQP | AAQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Xin actin-binding repeat-containing protein 1
    ELISA Kit for Human Xin actin-binding repeat-containing protein 1
    ELISA Kit for Human Xin actin-binding repeat-containing protein 1
    CLIA Kit for Human Xin actin-binding repeat-containing protein 1
    CLIA Kit for Human Xin actin-binding repeat-containing protein 1
    CLIA Kit for Human Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 1
    Protein for Human Xin actin-binding repeat-containing protein 1
    Protein for Human Xin actin-binding repeat-containing protein 1
    Protein for Human Xin actin-binding repeat-containing protein 1

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    Precision
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B);FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH F-ACTIN
      tissue: Skeletal muscle.
    2. 2.
      "Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP."
      van der Ven P.F.M. , Ehler E. , Vakeel P. , Eulitz S. , Schenk J.A. , Milting H. , Micheel B. , Fuerst D.O.
      Exp. Cell Res.312:2154-2167(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);ALTERNATIVE SPLICING (ISOFORMS B AND C);TISSUE SPECIFICITY;INTERACTION WITH FLNC AND VASP
      tissue: Skeletal muscle.
    3. 3.
      "A novel human gene, hXin, specifically expressed in human heart and skeletal muscle."
      Luo J. , Liu M. , Wu X.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 444-1843 (ISOFORM A)
      tissue: Heart.
      tissue: Tongue.
      tissue: Trachea.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 570-1623 (ISOFORM A);VARIANT ARG-346
      tissue: Liver.
      tissue: Skeletal muscle.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C);VARIANT ARG-1604
    7. 7.
      "Study of a muscle specific transcript."
      Trevisan S. , Lanfranchi G.
      Submitted (2000-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1554-1843
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] HIS-929 AND LYS-1634
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