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Index > Protein center > XIRP2(Gene name) > Human
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  • XIRP2 (Gene name),
  • Xin actin-binding repeat-containing protein 2 (Protein name ),  XIRP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    XIRP2(CMYA3);
    Protein name:
    Xin actin-binding repeat-containing protein 2;
    Alternative:
    Cardiomyopathy-associated protein 3;Beta-xin;Xeplin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with ACTN2 (By similarity). Interacts with F-actin.
    Function:
    Protects actin filaments from depolymerization.
    Subcellular Location:
    Cell junction Colocalizes with actin stress fibers.
    Protein Attributes:
    Sequence length:
    3374
    Sequence:
    50:
    MSPESGHSRI | FEATAGPNKP | ESGFAEDSAA | RGEGVSDLHE | VVSLKERMAR | 
    100:
    YQAAVSRGDC | RSFSANMMEE | SEMCAVPGGL | AKVKKQFEDE | ITSSRNTFAQ | 
    150:
    YQYQHQNRSE | QEAIHSSQVG | TSRSSQEMAR | NEQEGSKVQK | IDVHGTEMVS | 
    200:
    HLEKHTEEVN | QASQFHQYVQ | ETVIDTPEDE | EIPKVSTKLL | KEQFEKSAQE | 
    250:
    KILYSDKEMT | TPAKQIKTES | EYEETFKPSS | VVSTSSTSCV | STSQRKETST | 
    300:
    TRYSDHSVTS | STLAQINATS | SGMTEEFPPP | PPDVLQTSVD | VTAFSQSPEL | 
    350:
    PSPPRRLPVP | KDVYSKQRNL | YELNRLYKHI | HPELRKNLEK | DYISEVSEIV | 
    400:
    SSQMNSGSSV | SADVQQARYV | FENTNDSSQK | DLNSEREYLE | WDEILKGEVQ | 
    450:
    SIRWIFENQP | LDSINNGSPD | EGDISRGIAD | QEIIAGGDVK | YTTWMFETQP | 
    500:
    IDTLGAYSSD | TVENAEKIPE | LARGDVCTAR | WMFETRPLDS | MNKMHQSQEE | 
    550:
    SAVTISKDIT | GGDVKTVRYM | FETQHLDQLG | QLHSVDEVHL | LQLRSELKEI | 
    600:
    KGNVKRSIKC | FETQPLYVIR | DGSGQMLEIK | TVHREDVEKG | DVRTARWMFE | 
    650:
    TQPLDTINKD | ITEIKVVRGI | SMEENVKGGV | SKAKWLFETQ | PLEKIKESEE | 
    700:
    VIIEKEKIIG | TDVSRKCWMF | ETQPLDILKE | VPDADSLQRE | EIIGGDVQTT | 
    750:
    KHLFETLPIE | ALKDSPDIGK | LQKITASEEE | KGDVRHQKWI | FETQPLEDIR | 
    800:
    KDKKEYTRTV | KLEEVDRGDV | KNYTHIFESN | NLIKFDASHK | IEVEGVTRGA | 
    850:
    VELNKSLFET | TPLYAIQDPL | GKYHQVKTVQ | QEEIVRGDVR | SCRWLFETRP | 
    900:
    IDQFDESIHK | FQIIRGISAQ | EIQTGNVKSA | KWLFETQPLD | SIKYFSDVEE | 
    950:
    TESKTEQTRD | IVKGDVKTCK | WLFETQPMES | LYEKVSLMTS | SEEIHKGDVK | 
    1000:
    TCTWLFETQP | LDTIKDDSET | AVKLQTVKQE | EIQGGDVRTA | CFLFETENLD | 
    1050:
    SIQGEEVKEI | KPVEMDIQAG | DVSSMRYKFE | NQSLDSISSS | SEEVLKKIKT | 
    1100:
    LKTEDIQKGN | VLNCRWLFEN | QPIDKIKESQ | EGDECVKTVT | DIQGGDVRKG | 
    1150:
    CFIFETFSLD | EIKEESDYIS | TKKTITEEVI | QGDVKSYRML | FETQPLYAIQ | 
    1200:
    DREGSYHEVT | TVKKEEVIHG | DVRGTRWLFE | TKPLDSINKS | ETVYVIKSVT | 
    1250:
    QEDIQKGDVS | SVRYRFETQP | LDQISEESHN | IMPSIDHIQG | GNVKTSRQFF | 
    1300:
    ESENFDKNNY | IRTVSVNEIQ | KGNVKTSTWL | FETHTMDELR | GEGLEYENIK | 
    1350:
    TVTQEDVQKG | DVKQAVWLFE | NRTFDSIMEA | HKGITKMTKE | EIPPSDVKTT | 
    1400:
    TWLFETTPLH | EFNETRVEKI | EIIGKSIKET | LEDLYSQKVI | QAPGIIIEAD | 
    1450:
    EIGDVRMAKY | KLMNQASPEI | QKEEIIRADL | RNIMVNLLSK | RDCTEREILI | 
    1500:
    SEEEKGNVNL | TKTQLLNRST | EFHAEKEEIV | KGDVQQAIKN | LFSEERSVKK | 
    1550:
    GILIQEDEKG | DINMTIYCLL | HENDGDTIER | EEVIGGDVKR | TIHNLLSSTS | 
    1600:
    NNKISERAKI | DASERGNVQF | FTTCIEAGAL | DYLKQLHTES | NETLTAKKQE | 
    1650:
    GEKEIIGGDV | EGTKLLLKKR | QSLVERTVSE | TDIIPGDVHN | TVKVFMTEPQ | 
    1700:
    STFGKIPKEE | IIKGDLTSTL | NSLSQAVNQK | TVTKTEEIIK | GNMLATLKSL | 
    1750:
    KESSHRWKES | KQPDAIPGDI | EKAIECLEKA | TNTKTEILKK | ELLKDDLETS | 
    1800:
    LRSLKEAQRS | FKEVHKEGVI | KKDAKAVMAG | SSGEQKTDIH | QVAVQRNKNS | 
    1850:
    LLQPKPGPFE | PAAKWQGGAD | TLSQTMGKSC | HGNLVEERTE | VNLPKAPKGT | 
    1900:
    VKIVIDREQN | NDALEKSLRR | LSNSHHKSNV | LESGDKTGVW | TDTTGEQHLR | 
    1950:
    DEYMSRQLTS | TVSVKNNLTT | KESDRAVREL | KKDDVFNSIQ | SAGKTVGKQQ | 
    2000:
    TYELRNDHQK | MEGFHIKSPK | KTKNIKILTD | TQSSKPSPTQ | HPVSMPVGGT | 
    2050:
    YDLSGDFQKQ | TLLKQETKYS | NKDIKKKNIN | LQPMWQLLPV | EQDTSNVTEM | 
    2100:
    KVSEKSHNTF | KATNKKRETD | VHLKSQDFLM | KTNTSTGLKM | AMERSLNPIN | 
    2150:
    FNPENNVKES | ECPLPPPSPP | PPPPSNASSE | IEFPLPPPPP | LMMFPEKNGF | 
    2200:
    LPSLSTEKIK | AEFESFPGLP | LPPPPVDEKS | ERESSSMFLP | PPPPPTPSQK | 
    2250:
    PAHLLSSSAP | EKHSGDFMQQ | YSQKEASNSQ | NSQAKIITGK | TGVLPPPTLP | 
    2300:
    KPKLPKHIKD | NKNDFSPKVE | LATSLSDMEC | KITTSKDQKK | VMVMTSSEHT | 
    2350:
    ETKQNVISKS | LDERKQLSID | SANCLSHTVP | GTSAPRKKQI | APLIKSHSFP | 
    2400:
    ESSGQQNPKP | YMRKFKTPLM | IAEEKYRQQK | EEIEKQKQES | SYYNIVKTQS | 
    2450:
    QNQHITEVEK | EMPLQKTNEE | VSLSGIDSEC | TVVQPSPGSQ | SNARILGVCS | 
    2500:
    DNQLSTTSPE | TVAAKRLHHV | LAASEDKDKM | KKEVLQSSRD | IMQSKSACEI | 
    2550:
    KQSHQECSTQ | QTQQKKYLEQ | LHLPQSKPIS | PNFKVKTIKL | PTLDHTLNET | 
    2600:
    DHSYESHKQQ | SEIDVQTFTK | KQYLKTKKTE | ASTECSHKQS | LAERHYQLPK | 
    2650:
    KEKRVTVQLP | TESIQKNQED | KLKMVPRKQR | EFSGSDRGKL | PGSEEKNQGP | 
    2700:
    SMIGRKEERL | ITERKHEHLK | NKSAPKVVKQ | KVIDAHLDSQ | TQNFQQTQIQ | 
    2750:
    TAESKAEHKK | LPQPYNSLQE | EKCLEVKGIQ | EKQVFSNTKD | SKQEITQNKS | 
    2800:
    FFSSVKESQR | DDGKGALNIV | EFLRKREELQ | QILSRVKQFE | AEPNKSGLKT | 
    2850:
    FQTLLNTIPG | WLISEDKREY | AVHIAMENNL | EKVKEEITHI | KTQAEDMLVS | 
    2900:
    YENIIQTAMM | SSKTGKPGNK | PTSLDETSSK | VSNVHVSNNK | NSEQKENKIA | 
    2950:
    KEKTVQHQVA | AHHEATVRSH | VKTHQEIKLD | DSNIPPPSLK | TRPPSPTFIT | 
    3000:
    IESTARRTEN | PTKNELSQSP | KKDSYVEPPP | RRPMSQKSEI | HRANTSPSPP | 
    3050:
    RSRSEQLVRL | KDTTAKLSKG | AIPCPAATPV | PIVEKRSEII | MSPATLRRQI | 
    3100:
    KIETRGRDSP | PTITIPVNIN | HAASGSFRES | VDAQEEIRKV | EKRATYVHKD | 
    3150:
    GLNSTDHMVP | DTESYDAVEI | IRKVAVPPRL | SEHTQRYEAA | NRTVQMAENF | 
    3200:
    VNDPENEINR | WFREFEHGPV | SEAKSNRRVY | AKGETNHNIQ | QESRTFCKEE | 
    3250:
    FGLTSLGNTS | FTDFSCKHPR | ELREKIPVKQ | PRICSETRSL | SEHFSGMDAF | 
    3300:
    ESQIVESKMK | TSSSHSSEAG | KSGCDFKHAP | PTYEDVIAGH | ILDISDSPKE | 
    3350:
    VRKNFQKTWQ | ESGRVFKGLG | YATADASATE | MRTTFQEESA | FISEAAAPRQ | 
    3374:
    GNMYTLSKDS | LSNGVPSGRQ | AEFS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Xin actin-binding repeat-containing protein 2
    ELISA Kit for Human Xin actin-binding repeat-containing protein 2
    ELISA Kit for Human Xin actin-binding repeat-containing protein 2
    CLIA Kit for Human Xin actin-binding repeat-containing protein 2
    CLIA Kit for Human Xin actin-binding repeat-containing protein 2
    CLIA Kit for Human Xin actin-binding repeat-containing protein 2
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Polyclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Monoclonal Antibody for Human Xin actin-binding repeat-containing protein 2
    Protein for Human Xin actin-binding repeat-containing protein 2
    Protein for Human Xin actin-binding repeat-containing protein 2
    Protein for Human Xin actin-binding repeat-containing protein 2

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    References
    1. 1.
      "A novel gene containing a Xin repeat."
      Luo J. , Liu M. , Wu X.
      Submitted (2004-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    2. 2.
      "bXin: genes, splice variants and cellular distribution of a family of proteins implicated."
      Wang K. , Xie L. , Tsai W.L. , Gutierrez-Cruz G.
      Submitted (2006-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 4; 6 AND 7)
      tissue: Heart.
      tissue: Testis.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 901-1683 (ISOFORMS 1/2/3)
      tissue: Tongue.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 112-748 (ISOFORMS 1/2/3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 3177-3374 (ISOFORMS 1/2)
      tissue: Skeletal muscle.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 361-1380 (ISOFORMS 1/2/3);FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH F-ACTIN
      tissue: Skeletal muscle.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 439-3374 (ISOFORMS 1/2)
      tissue: Skeletal muscle.
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