YES1 ELISA Kit for Human(Homo sapiens) | EIAab.comYES1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > YES1(Gene name) > Human

YES1 (Gene name),

Tyrosine-protein kinase Yes (Protein name ), YES_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

YES1(YES);

Protein name:

Tyrosine-protein kinase Yes;

Alternative:

p61-Yes;Proto-oncogene c-Yes;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with FASLG.

Function:

Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.

Subcellular Location:

Cytoplasm cytosol In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.

Protein Attributes:

Sequence length:

543

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

543:

LHELMNLCWK | KDPDERPTFE | YIQSFLEDYF | TATEPQYQPG | ENL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.194148

MIM:

164880

String:

P07947

Pfam:

PF07714

STRING:

9606.ENSP00000324740

SMR:

P07947

KEGG:

hsa:7525

Uniprot:

P07947

FOR

ELISA Kit for Human Tyrosine-protein kinase Yes

CLIA Kit for Human Tyrosine-protein kinase Yes

Polyclonal Antibody for Human Tyrosine-protein kinase Yes

Monoclonal Antibody for Human Tyrosine-protein kinase Yes

Protein for Human Tyrosine-protein kinase Yes

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of cDNA clones for the human c-yes gene."
Sukegawa J. , Semba K. , Yamanashi Y. , Nishizawa M. , Miyajima N. , Yamamoto T. , Toyoshima K.
Mol. Cell. Biol.7:41-47(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"DNA sequence and analysis of human chromosome 18."
Nusbaum C. , Zody M.C. , Borowsky M.L. , Kamal M. , Kodira C.D. , Taylor T.D. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Abouelleil A. , Allen N.R. , Anderson S. , Bloom T. , Bugalter B. , Butler J. , more...
Nature437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
5.

"Distribution of c-yes-1 gene product in various cells and tissues."
Sugawara K. , Sugawara I. , Sukegawa J. , Akatsuka T. , Yamamoto T. , Morita M. , Mori S. , Toyoshima K.
Br. J. Cancer63:508-513(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"Differential expression of p62c-yes in normal, hyperplastic and neoplastic human epidermis."
Krueger J. , Zhao Y.H. , Murphy D. , Sudol M.
Oncogene6:933-940(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
7.

"Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif."
Koegl M. , Zlatkine P. , Ley S.C. , Courtneidge S.A. , Magee A.I.
Biochem. J.303:749-753(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION
8.

"Expression, purification, and initial characterization of human Yes protein tyrosine kinase from a bacterial expression system."
Sun G. , Budde R.J.
Arch. Biochem. Biophys.345:135-142(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY CSK
9.

"Autophosphorylation of Src and Yes blocks their inactivation by Csk phosphorylation."
Sun G. , Sharma A.K. , Budde R.J.
Oncogene17:1587-1595(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-426;MUTAGENESIS OF TYR-426
10.

"CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae."
Lee S.W. , Bonnah R.A. , Higashi D.L. , Atkinson J.P. , Milgram S.L. , So M.
J. Cell Biol.156:951-957(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION;FUNCTION
11.

"c-Yes response to growth factor activation."
Clump D.A. , Qazi I.H. , Sudol M. , Flynn D.C.
Growth Factors23:263-272(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
12.

"Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases."
Martin N.G. , McAndrew P.C. , Eve P.D. , Garrett M.D.
FEBS J.275:3099-3109(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF CDK4
13.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-537;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-21 AND SER-40;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
15.

"Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening."
Voss M. , Lettau M. , Janssen O.
BMC Immunol.10:53-53(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FASLG
16.

"Phosphorylation of collapsin response mediator protein 2 on Tyr-479 regulates CXCL12-induced T lymphocyte migration."
Varrin-Doyer M. , Vincent P. , Cavagna S. , Auvergnon N. , Noraz N. , Rogemond V. , Honnorat J. , Moradi-Ameli M. , Giraudon P.
J. Biol. Chem.284:13265-13276(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF DPYSL2
17.

"Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain."
Sato I. , Obata Y. , Kasahara K. , Nakayama Y. , Fukumoto Y. , Yamasaki T. , Yokoyama K.K. , Saito T. , Yamaguchi N.
J. Cell Sci.122:965-975(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
18.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-336; TYR-345 AND TYR-537;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
19.

"Clues for c-Yes involvement in the cell cycle and cytokinesis."
Jung J. , Lee M.K. , Jin Y. , Fu S.B. , Rosales J.L. , Lee K.Y.
Cell Cycle10:1502-1503(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
20.

"The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway."
Tauzin S. , Chaigne-Delalande B. , Selva E. , Khadra N. , Daburon S. , Contin-Bordes C. , Blanco P. , Le Seyec J. , Ducret T. , Counillon L. , Moreau J.F. , Hofman P. , Vacher P. , Legembre P.
PLoS Biol.9:E1001090-E1001090(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
21.

"Crystallographic structure of the SH3 domain of the human c-Yes tyrosine kinase: loop flexibility and amyloid aggregation."
Martin-Garcia J.M. , Luque I. , Mateo P.L. , Ruiz-Sanz J. , Camara-Artigas A.
FEBS Lett.581:1701-1706(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 91-152
22.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] VAL-198 AND ARG-282

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