Tjp1 ELISA Kit for Mouse(Mus musculus) | EIAab.comTjp1 ELISA Kit for Mouse(Mus musculus)

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Tjp1 (Gene name),

Tight junction protein ZO-1 (Protein name ), ZO1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tjp1(Zo1);

Protein name:

Tight junction protein ZO-1;

Alternative:

Zona occludens protein 1;Tight junction protein 1;Zonula occludens protein 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer, and heterodimer with TJP2/ZO-2 and TJP3/ZO-3. Interacts with CGN/cingulin, CALM, CXADR, GJD3, HSPA4 and UBN1. Interacts (via ZU5 domain) with CDC42BPB. Interacts (via PDZ domain) with GJA1 (By similarity). Interacts with OCLN, claudins, GJA12 and KIRREL1. Interacts with BVES (via the C-terminus cytoplasmic tail). Interacts (via ZU5 domain) with GCOM1.

Function:

The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.

Subcellular Location:

Cell membrane Peripheral membrane protein Cytoplasmic side Cell junction tight junction Cell junction gap junction Cytoplasm myofibril sarcomere I band Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.

Protein Attributes:

Sequence length:

1745

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1745:

GLKFLKPVEL | RLPHCDPKTW | QNKCLPGDPN | YLVGANCVSV | LIDHF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00625

SMR:

P39447

STRING:

10090.ENSMUSP00000032729

String:

P39447

UniGene:

Mm.4342

KEGG:

mmu:21872

Uniprot:

P39447

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ELISA Kit for Mouse Tight junction protein ZO-1

Cat.:

E9600h

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Manual:

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96T

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ELISA Kit for Mouse Tight junction protein ZO-1

Cat.:

E9600d

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96T

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ELISA Kit for Mouse Tight junction protein ZO-1

Cat.:

E9600m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Mouse Tight junction protein ZO-1

Cat.:

U9600h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Tight junction protein ZO-1

Cat.:

U9600m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Tight junction protein ZO-1

Cat.:

U9600d

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Tight junction protein ZO-1

Cat.:

P9600Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Tight junction protein ZO-1

Cat.:

P9600Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Tight junction protein ZO-1

Protein for Mouse Tight junction protein ZO-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The 220-kD protein colocalizing with cadherins in non-epithelial cells is identical to ZO-1, a tight junction-associated protein in epithelial cells: cDNA cloning and immunoelectron microscopy."
Itoh M. , Nagafuchi A. , Yonemura S. , Yasuda-Kitani T. , Tsukita S. , Tsukita S.
J. Cell Biol.121:491-502(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: 129.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"NEPH1 defines a novel family of podocin interacting proteins."
Sellin L. , Huber T.B. , Gerke P. , Quack I. , Pavenstaedt H. , Walz G.
FASEB J.17:115-117(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KIRREL1
strain: Swiss Webster.
tissue: Brain.
4.

"Connexin47, connexin29 and connexin32 co-expression in oligodendrocytes and Cx47 association with zonula occludens-1 (ZO-1) in mouse brain."
Li X. , Ionescu A.V. , Lynn B.D. , Lu S. , Kamasawa N. , Morita M. , Davidson K.G.V. , Yasumura T. , Rash J.E. , Nagy J.I.
Neuroscience126:611-630(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GJA12;DOMAIN
5.

"Bves modulates epithelial integrity through an interaction at the tight junction."
Osler M.E. , Chang M.S. , Bader D.M.
J. Cell Sci.118:4667-4678(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BVES
6.

"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
7.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
8.

"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
Cao L. , Yu K. , Banh C. , Nguyen V. , Ritz A. , Raphael B.J. , Kawakami Y. , Kawakami T. , Salomon A.R.
J. Immunol.179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1139 AND TYR-1353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Mast cell.
9.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-912;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
10.

"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H. , Ye M. , Dong J. , Han G. , Jiang X. , Wu R. , Zou H.
J. Proteome Res.7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-912;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
11.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1164;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
12.

"Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo."
Seeger T.S. , Frank D. , Rohr C. , Will R. , Just S. , Grund C. , Lyon R. , Luedde M. , Koegl M. , Sheikh F. , Rottbauer W. , Franke W.W. , Katus H.A. , Olson E.N. , Frey N.
Circ. Res.106:880-890(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYZAP;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
13.

"(1)H, (13)C, and (15)N resonance assignment of the first PDZ domain of mouse ZO-1."
Umetsu Y. , Goda N. , Taniguchi R. , Satomura K. , Ikegami T. , Furuse M. , Hiroaki H.
Biomol. NMR. Assign.5:207-210(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 18-110

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