EDN1 ELISA Kit for Human(Homo sapiens) | EIAab.comEDN1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > EDN1(Gene name) > Human

EDN1 (Gene name),

Endothelin-1 (Protein name ), EDN1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (3)

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Gene name:

EDN1;

Protein name:

Endothelin-1;

Alternative:

C-terminal pro endothelin-1(CT-proET1);Preproendothelin-1(PPET1);

Organism:

EDN1 (Homo sapiens).

General Annotation

Sub Unit:

Function:

Endothelins are endothelium-derived vasoconstrictor peptides.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

212

Sequence:

50:

100:

150:

200:

212:

RERYVTHNRA | HW

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P05305

UniGene:

Hs.511899

KEGG:

hsa:1906

MIM:

131240

Pfam:

PF00322

STRING:

9606.ENSP00000368683

Uniprot:

P05305

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ELISA Kit for Human Endothelin-1

Cat.:

E0482h

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96T

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ELISA Kit for Human Endothelin-1

Cat.:

E0482r

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96T

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ELISA Kit for Human Endothelin-1

Cat.:

E0482m

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96T

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ELISA Kit for Human Endothelin-1

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ELISA Kit for Human Endothelin-1

Cat.:

E0482b

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96T

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ELISA Kit for Human Endothelin-1

Cat.:

E0482d

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Packing:

96T

ELISA Kit for Human Endothelin-1

Cat.:

E0482p

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Packing:

96T

CLIA Kit for Human Endothelin-1

Cat.:

U0482d

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96T

CLIA Kit for Human Endothelin-1

Cat.:

U0482h

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96T

CLIA Kit for Human Endothelin-1

Cat.:

U0482p

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96T

CLIA Kit for Human Endothelin-1

Cat.:

U0482b

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Packing:

96T

CLIA Kit for Human Endothelin-1

MSDS:

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CLIA Kit for Human Endothelin-1

Cat.:

U0482m

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Looking for manual.

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96T

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CLIA Kit for Human Endothelin-1

Cat.:

U0482r

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96T

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Polyclonal Antibody for Human Endothelin-1

Cat.:

P0482Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Endothelin-1

Cat.:

P0482Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Endothelin-1

Cat.:

P0482Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human Endothelin-1

Protein for Human Endothelin-1

Cat.:

R0482h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human Endothelin-1

R&D Technical Data

12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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Citations

[1].

"Relation of locus 1p13 rs646776 polymorphism with the risk of preeclampsia"

R H. Emam, M H. Ghattas, N M. Mesbah, et al.

From:Hypertension in Pregnancy

[2].

"Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells"

JS Ouyang, YP Li, CY Li, C Cai, CS Chen, SX Chen, YF Chen, L Yang, YP Xie

From:Free Radical Research

[3].

"Adipokine, adropin and endothelin-1 levels in intrauterine growth restricted neonates and their mothers"

Aydin H I, Eser A, Kaygusuz I, et al.

From:Journal of perinatal medicine

References

1.

"Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin."
Itoh Y. , Yanagisawa M. , Ohkubo S. , Kimura C. , Kosaka T. , Inoue A. , Ishida N. , Mitsui Y. , Onda H. , Fujino M. , Masaki T.
FEBS Lett.231:440-444(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
2.

"The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression."
Inoue A. , Yanagisawa M. , Takuwa Y. , Mitsui Y. , Kobayashi M. , Masaki T.
J. Biol. Chem.264:14954-14959(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Structural organization and chromosomal assignment of the gene encoding endothelin."
Bloch K.D. , Friedrich S.P. , Lee M.E. , Eddy R.L. , Shows T.B. , Quertermous T.
J. Biol. Chem.264:10851-10857(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Two preproendothelin 1 mRNAs transcribed by alternative promoters."
Benatti L. , Bonecchi L. , Cozzi L. , Sarmientos P.
J. Clin. Invest.91:1149-1156(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

NIEHS SNPs program
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASN-198
6.

"The DNA sequence and analysis of human chromosome 6."
Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ASN-198
tissue: Pancreas.
8.

"The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes."
Inoue A. , Yanagisawa M. , Kimura S. , Kasuya Y. , Miyauchi T. , Goto K. , Masaki T.
Proc. Natl. Acad. Sci. U.S.A.86:2863-2867(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 27-67
9.

"Proteolytic processing of big endothelin-3 by the kell blood group protein."
Lee S. , Lin M. , Mele A. , Cao Y. , Farmar J. , Russo D. , Redman C.
Blood94:1440-1450(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;CLEAVAGE BY KELL;IDENTIFICATION BY MASS SPECTROMETRY
10.

"The signal peptide of human preproendothelin-1."
Fabbrini M.S. , Valsasina B. , Nitti G. , Benatti L. , Vitale A.
FEBS Lett.286:91-94(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
11.

"Endothelin-1 and ETA receptor expression in vascular smooth muscle cells from human placenta: a new ETA receptor messenger ribonucleic acid is generated by alternative splicing of exon 3."
Bourgeois C. , Robert B. , Rebourcet R. , Mondon F. , Mignot T.-M. , Duc-Goiran P. , Ferre F.
J. Clin. Endocrinol. Metab.82:3116-3123(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
12.

"Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol."
Pare G. , Serre D. , Brisson D. , Anand S.S. , Montpetit A. , Tremblay G. , Engert J.C. , Hudson T.J. , Gaudet D.
Am. J. Hum. Genet.80:673-682(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-198;CHARACTERIZATION OF VARIANT ASN-198
13.

"Investigating the association between K198N coding polymorphism in EDN1 and hypertension, lipoprotein levels, the metabolic syndrome and cardiovascular disease."
Wiltshire S. , Powell B.L. , Jennens M. , McCaskie P.A. , Carter K.W. , Palmer L.J. , Thompson P.L. , McQuillan B.M. , Hung J. , Beilby J.P.
Hum. Genet.123:307-313(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-198
14.

"Crystallization and preliminary X-ray analysis of human endothelin."
Wolff M. , Day J. , Greenwood A. , Larson S. , McPherson A.
Acta Crystallogr. B48:239-240(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF ET-1
15.

"The crystal structure of human endothelin."
Janes R.W. , Peapus D.H. , Wallace B.A.
Nat. Struct. Biol.1:311-319(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.18 ANGSTROMS) OF ET-1;DISULFIDE BONDS
16.

"The conformation of endothelin-1 in aqueous solution: NMR-derived constraints combined with distance geometry and molecular dynamics calculations."
Reily M.D. , Dunbar J.B. Jr.
Biochem. Biophys. Res. Commun.178:570-577(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF ET-1
17.

"Conformational isomerism of endothelin in acidic aqueous media: a quantitative NOESY analysis."
Andersen N.H. , Chen C. , Marschner T.M. , Krystek S.R. Jr. , Bassolino D.A.
Biochemistry31:1280-1295(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF ET-1
18.

"Solution conformation of human big endothelin-1."
Donlan M.L. , Brown F.K. , Jeffs P.W.
J. Biomol. NMR2:407-420(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 53-90
19.

"A comparison of X-ray and NMR structures for human endothelin-1."
Wallace B.A. , Janes R.W. , Bassolino D.A. , Krystek S.R. Jr.
Protein Sci.4:75-83(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPARISON OF NMR STRUCTURE WITH X-RAY STRUCTURE
20.

"Solution structure of a novel ETB receptor selective agonist ET1-21 [Cys(Acm)1,15, Aib3,11, Leu7] by nuclear magnetic resonance spectroscopy and molecular modelling."
Hewage C.M. , Jiang L. , Parkinson J.A. , Ramage R. , Sadler I.H.
J. Pept. Res.53:223-233(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF ET1 AGONIST
21.

"The Lys198Asn polymorphism in the endothelin-1 gene is associated with blood pressure in overweight people."
Tiret L. , Poirier O. , Hallet V. , McDonagh T.A. , Morrison C. , McMurray J.J. , Dargie H.J. , Arveiler D. , Ruidavets J.B. , Luc G. , Evans A. , Cambien F.
Hypertension33:1169-1174(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-198
22.

"Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis."
Halushka M.K. , Fan J.-B. , Bentley K. , Hsie L. , Shen N. , Weder A. , Cooper R. , Lipshutz R. , Chakravarti A.
Nat. Genet.22:239-247(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-198
23.

"Mutations in endothelin 1 cause recessive auriculocondylar syndrome and dominant isolated question-mark ears."
Gordon C.T. , Petit F. , Kroisel P.M. , Jakobsen L. , Zechi-Ceide R.M. , Oufadem M. , Bole-Feysot C. , Pruvost S. , Masson C. , Tores F. , Hieu T. , Nitschke P. , Lindholm P. , Pellerin P. , Guion-Almeida M.L. , Kokitsu-Nakata N.M. , Vendramini-Pittoli S. , Munnich A. , more...
Am. J. Hum. Genet.93:1118-1125(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT QME ASP-64;VARIANTS ARCND3 HIS-77 AND GLU-91

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